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ProteomicsAn extracellular receptor tyrosine kinase motif orchestrating intracellular STAT activation
The ErbB4 receptor isoforms JM-a and JM-b differ within their extracellular juxtamembrane (eJM) domains. Here, ErbB4 isoforms are used as a model to address the effect of structural variation in the eJM domain of receptor tyrosine kinases (RTK) on downstream signaling. A specific JM-a-like sequence ...
ORGANISM(S): Homo sapiens (Human) 
2023-01-30 | PXD026546 | Pride
Receptor tyrosine kinase Jm-a Rtk Stat signaling Erbb4 Jm-b 
ProteomicsSTAT5b is a key effector of NRG-1/ERBB4-mediated cardiomyocyte growth
Interactome of ErbB4 JM-a and JM-b in MDA-MB-468 cells.
ORGANISM(S): Homo sapiens (Human) 
2023-02-20 | PXD040166 | Pride
Stat5 Interactome Erbb4 Nrg-1 Lc-msms Cardiomyocyte 
ProteomicsAn extracellular receptor tyrosine kinase motif orchestrating intracellular STAT activation
The ErbB4 receptor isoforms JM-a and JM-b differ within their extracellular juxtamembrane (eJM) domains. Here, ErbB4 isoforms are used as a model to address the effect of structural variation in the eJM domain of receptor tyrosine kinases (RTK) on downstream signaling. A specific JM-a-like sequence ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) Cercopithecus aethiops (Green monkey) (Grivet) 
2023-01-30 | PXD017783 | Pride
N-lectin Streptavidin pull down 
ProteomicsTargeted validation of interaction between ErbB4 JM-a isoform and β1 integrin
The ErbB4 receptor isoforms JM-a and JM-b differ within their extracellular juxtamembrane (eJM) domains. Here we used ErbB4 isoforms as a model to address whether structural variation in the eJM domain of receptor tyrosine kinases (RTK) affects downstream signaling. Analysis of ErbB4 interactome and...
ORGANISM(S): Homo Sapiens 
2022-10-22 | PXD026617 | panorama
UnknownCell death or survival promoted by alternative isoforms of ErbB4.
Not available
S-EPMC2993754 | biostudies-literature
UnknownAn extracellular receptor tyrosine kinase motif orchestrating intracellular STAT activation.
Not available
S-EPMC9663514 | biostudies-literature
UnknownThe prognostic value of Her4 receptor isoform expression in triple-negative and Her2 positive breast cancer patients.
Not available
S-EPMC3849049 | biostudies-literature
TranscriptomicsDistinct genetic alterations occur in ovarian tumor cells selected for combined resistance to carboplatin and docetaxel
Background: Current protocols for the treatment of ovarian cancer include combination chemotherapy with a platinating agent and a taxane. However, many patients experience relapse of their cancer and the development of drug resistance is not uncommon, making successful second line therapy difficult ...
ORGANISM(S): Homo sapiens 
2013-07-22 | E-GEOD-39337 | biostudies-arrayexpress
TranscriptomicsLongSAGE analysis of wild-type mouse brain regions
LongSAGE libraries generated from various brain regions of 8- to 12-week-old male C57BL/6 mice. Keywords: Micro-dissection, Brain regions, SAGE Sau3A I was used as the anchoring enzyme and Mme I as the tagging enzyme. Data are provided after linker removal.
ORGANISM(S): Mus musculus 
2008-02-05 | E-GEOD-7593 | biostudies-arrayexpress
TranscriptomicsSAGE analysis of wild-type mouse brain regions
SAGE libraries generated from various brain regions of 8- to 12-week-old male C57BL/6 mice. Keywords: Micro-dissection, Brain regions, SAGE Sau3A I was used as the anchoring enzyme and Bsmf I as the tagging enzyme. Data are provided after linker removal.
ORGANISM(S): Mus musculus 
2008-02-05 | E-GEOD-7594 | biostudies-arrayexpress
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