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Stress Granule formation has been linked to the resistance of some cancer cells to chemotherapeutic intervention. A number of studies have proposed that certain anti-tumor compounds promote cancer cell survival by inducing Stress Granules formation, leading to increased cellular fitness and apoptosi...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021229 | Pride
Identification of Stress Granule interacting proteins by BioID (Roux et al., 2012) using PABPC1-BirA(R118G)-GFP construct
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD025334 | Pride
We investigated the sub-cellular architecture of Stress Granules in the context of glucose starvation. In order to uncover transient and peripheral Stress Granule interactors, we optimized the proximity-dependent biotinylation (BioID) approach for use in yeast. This approach allowed us to visualize ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-03-23 | PXD016988 | Pride
We investigated eisosome rearrangement during glucose starvation. Pil1 phosphorylation was assessed in control and starvation conditions.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-03-23 | PXD017502 | Pride
The eukaryotic cytoplasmic chaperonin-containing TCP-1 (CCT) is a complex formed by two back-to-back stacked hetero-octameric rings that assists the folding of actins, tubulins and other proteins in an ATP-dependent manner. Here, we decided to test the significance of the hetero-oligomeric nature o...
ORGANISM(S): Saccharomyces cerevisiae 
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