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ProteomicsComprehensive evaluation of RNAlater effect on proteome and phosphoproteome
Tumors such as pancreatic cancer contain a variety of enzymes including DNases, RNases and proteases which may lead to autolysis of DNA, RNA and proteins during sample processing. In general, RNAlater can be used to keep nucleic acids intact since it contains high concentrations of quaternary ammoni...
ORGANISM(S): Homo sapiens (Human) 
2019-05-06 | PXD010710 | Pride
Rnalater Proteome Phosphoproteome 
ProteomicsAbl subtrates using tyrosine phosphoproteomics
In this study, we have prepared a mouse embryonic fibrobalst (MEF) cell line stably expressing R367A mutant human Abl in which the native mouse Abl1 and Abl2 were genetically deleted. We have used these R367A mutant Abl cells in combination with mass spectrometry to identify phosphorylation targets...
ORGANISM(S): Mus musculus (Mouse) 
2018-03-16 | PXD007118 | Pride
Silac Ptyr 
ProteomicsMissing proteins identified from the haploid cell lines: HAP1 and KBM-7
Chromosome-centric Human Proteomic Project (C-HPP) aims at identifying and characterizing protein products encoded from all protein-coding genes of human chromosomes. As evident in the recent nature papers, it is possible that those missing proteins may be low abundant in many cell types or expresse...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-10 | MSV000083952 | MassIVE
ProteomicsLung cancer and Normal Lung Tissue LC-MS/MS
The Chromosome-centric Human Proteome Project (C-HPP) was recently initiated as an international collaborative effort. Our team adopted chromosome 9 (Chr 9) and performed a bioinformatics and proteogenomic analysis to catalog Chr 9-encoded proteins from normal tissues, lung cancer cell lines and lun...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-12 | MSV000083969 | MassIVE
ProteomicsBALF proteomics - In-depth proteomic analysis of human bronchoalveolar lavage fluid towards the biomarker discovery for lung cancers
Lung cancer is one of the most common cancers and the leading cause of cancer-related mortality. Because the early diagnosis of the cancer is one of the major goals in lung cancer research, the molecule-based sensitive detection of biomarkers from bronchoalveolar lavage fluid (BALF) to diagnose the ...
ORGANISM(S): Homo sapiens (Human) 
2019-05-30 | PXD012645 | Pride
Balf Depletion Lung cancer 
ProteomicsCntnap2 KO mouse mPFC proteome for ASD
Autism Spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder where patients have impaired social behavior and communication, and restricted interests. Although various studies have been carried out to unveil the mechanisms associated with ASD, its pathophysiology is still poorly und...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD031656 | Pride
Cntnap2 Mpfc Mouse 
ProteomicsTime-resolved combined analysis of transcriptome and proteome of the pathogenicity-activated plant pathogen Xanthomonas oryzae pv. oryzae
Xanthomonas oryzae pv. oryzae (Xoo) is a rice pathogen causing bacterial blight, which outbreaks in most rice cultivating countries and reduces yield up to 50% due to no effective pesticide. Urgent responses of Xoo upon the initial contacts with rice at infection site are essential for pathogenesis....
ORGANISM(S): Xanthomonas oryzae pv. oryzae KACC 10331 
2021-09-09 | PXD020135 | Pride
Transcriptome Time-resolved gene expression Xoo–rice interactions Pathogenicity Proteome Xanthomonas oryzae pv. oryzae 
ProteomicsMetastatic pancreatic cancer signaling
Proteomic and signaling alterations among cells isolated from three sites of metastasis (liver, lung and peritoneum) from a single patient were studied using a SILAC-based quantitative proteomic strategy combined with a high resolution mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2014-08-13 | PXD000750 | Pride
Phosphotyrosine 
ProteomicsMissing proteins identified from the haploid cell lines: HAP1 and KBM-7
Chromosome-centric Human Proteomic Project (C-HPP) aims at identifying and characterizing protein products encoded from all protein-coding genes of human chromosomes. As evident in the recent nature papers, it is possible that those missing proteins may be low abundant in many cell types or expresse...
ORGANISM(S): Homo sapiens (Human) 
2018-10-01 | PXD006614 | Pride
Lc-msms Missing proteins Kbm-7 Haploid cell line Hap1 
OtherIdentifying novel targets of oncogenic EGF receptor signaling in lung cancer through global phosphoproteomics.
Data from ProteomeXchange, PXD ID: PXD001101. Experiment: pST_SILAC_R1a, file: H3255_pST_SILAC_R1_F4_a.mzml. Published as part of Proteomics. 2015 Jan;15(2-3):340-55 . From the Abstract: {{i}} . We sought to identify the immediate direct and indirect phosphorylation targets of mutant EGFRs in lung ...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320007613 | GPMDB
Resource Reanalysis 
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