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MetabolomicsMetabolomic Characterization of Knock-Out Mutants in Arabidopsis - Development of a Metabolite Profiling Database for Knock-Out Mutants in Arabidopsis (MeKO)
Despite recent intensive research efforts in functional genomics, the functions of only a limited number of Arabidopsis (Arabidopsis thaliana) genes have been determined experimentally. Thus, improving gene annotation remains a major challenge in plant science. Because metabolite profiling can chara...
2014-03-01 | MTBLS47 | MetaboLights
MetabolomicsChanges in lipid profiles of epileptic mouse model

INTRODUCTION: Approximately 1% of the world's population is impacted by epilepsy, a chronic neurological disorder characterized by seizures. One-third of epileptic patients are resistant to AEDs, or have medically refractory epilepsy (MRE). One non-invasive treatment that exists...

2022-01-06 | MTBLS1432 | MetaboLights
MetabolomicsMulti-omics analysis reveals immune-metabolic dysregulation in DNASE1L3-deficient mouse liver

This study investigates the role of DNASE1L3 deficiency in hepatic immune and metabolic regulation. Using transcriptomics, proteomics, and metabolomics, we characterize changes in Kupffer cell polarization, ER stress, iron metabolism, and ferroptosis in DNASE1L3 knockout mice.'

2025-10-25 | MTBLS13057 | MetaboLights
ProteomicsGPI-glycan structures of human Prion from knock-in mice_LC-MSMS
To determine glycosylphosphatidylinositol (GPI) structures of human prion proteins isolated from knock-in mice those express human prion protein instead of mouse one.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2020-04-22 | PXD017655 | Pride
Gpi Prion Gpi side-chain Brain Knock-in mouse Human 
ProteomicsGPI-glycan structures of human Prion (M232R) from knock-in mice_LC-MSMS
To determine glycosylphosphatidylinositol (GPI) structures of human prion proteins with M232R mutation isolated from knock-in mice those express human prion protein instead of mouse one.
ORGANISM(S): Homo sapiens (Human) 
2023-03-08 | PXD037584 | Pride
Gpi Gpi side chain Prion Brain Knock-in mouse Human 
ProteomicsA novel miniTurbo knock-in mouse reveals a protein interaction network of USP46 in the brain
To characterize the protein interaction network of USP46, BioID analysis was conducted on a knock-in cell line that expresses USP46 and biotin ligase fusion protein stably.
ORGANISM(S): Mus Musculus (mouse) 
2026-03-12 | PXD064961 | JPOST Repository
ProteomicsLC-MS/MS of SCA3 knock-in mouse cortex, cerebellum, and axons
Spinocerebellar ataxia type 3 (SCA3/MJD) has a polyQ etiology but, the current knowledge on molecular processes and proteins involved in pathogenesis is insufficient. Due to its proteolytic function, Ataxin-3 can influence other proteins, yet the global picture of crucial proteins and pathways in SC...
ORGANISM(S): Mus musculus (Mouse) 
2021-04-08 | PXD024945 | Pride
Ataxin-3 Brain Cerebellum Cag Axon Mjd Mouse Sca3 Cerebral cortex Lc-ms/ms Knock-in Knockin Spinocerebellar Ataxia Polyq Neurodegenerative Proteome 
GenomicsDysregulation of gene expression in SCGB3A2 Knock-out mouse
Dysregulation of gene expression in SCGB3A2 Knock-out mouse
PRJNA774254 | ENA
GenomicsGene expression profiles in GSK-3alpha Ser21Ala knock-in mouse heart
Gene expression profiles in GSK-3alpha Ser21Ala knock-in mouse heart
PRJNA442502 | ENA
GenomicsGene expression profiles in GSK-3beta Ser9Ala knock-in mouse heart
Gene expression profiles in GSK-3beta Ser9Ala knock-in mouse heart
PRJNA442503 | ENA
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