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ProteomicsElucidation of the role of murine lncRNA LL35 in hepatocytes by LC-MSMS
Long non-coding RNAs (lncRNAs) play important roles in the regulation of many biological processes in the cell like transcription, translation, splicing, transport, etc. More than 10K lncRNAs are predicted in human, but functions for the majority remain unknown. LncRNAs may contribute to the develop...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-11 | PXD033910 | Pride
Lc-msms Murine lncrna ll35 Aml12 cells 
UnknownHighly homogenous tri-acylated S-LPS acts as a novel clinically applicable vaccine against Shigella flexneri 2a infection.
Not available
S-EPMC6365007 | biostudies-literature
ProteomicsProteomic and phosphoproteomic changes upon overexpression of S. cerevisiae Ppz1 protein phosphatase
Over-expression of Ppz1 is deleterious for yeast cells. Recent studies in our laboratory demonstrated that the over-expression of a catalytically impaired version of Ppz1 (Ppz1R451L) is not toxic, suggesting that the excess of Ppz1 phosphatase activity was responsible for toxicity, possibly due to c...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-10-05 | PXD018100 | Pride
Yeast S. cerevisiae Phosphatase Antifungal target 
TranscriptomicsElucidation of stress memory inheritance through epigenome alterations in Brassica rapa plants [RNA-seq]
In the current study we have profiled changes in the transcriptome of somatic and reproductive tissues of B.rapa plants following heat shock stress exposure. For this we used Illumina GAIIx platform. We have demonstrated that the highest tissue-specific alterations in the transcriptome profile are d...
ORGANISM(S): Brassica rapa 
2014-12-04 | E-MTAB-4131 | biostudies-arrayexpress
ProteomicsAlternative Reading Frame expression in POLG gene
POLGARF is an upstream Alternative Reading Frame in POLG gene partially overlapping POLG sequence. To obtain POLGARF peptide reference spectra POLGARF was overexpressed in HEK293T and HEK293F cells .
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD016007 | Pride
Polg C1qbp Dual coding Uorf Leaky scanning Mir Cug 5’utr 
UnknownA Candidate Ac3-S-LPS Vaccine Against S. flexneri 1b, 2a, 3a, 6, and Y Activates Long-Lived Systemic and Mucosal Immune Responses in Healthy Volunteers: Results of an Open-Label, Randomized 2 Clinical Trial
Not available
S-EPMC11945589 | biostudies-literature
ProteomicsLiver proteome upon in vivo N-acetylgalactosamine-conjugated antisense oligonucleotide silencing of ceramide synthase 2
Mouse liver proteome was investigated upon in vivo mouse treatment with a N-acetylgalactosamine-conjugated antisense oligonucleotide engineered to silence ceramide synthase 2 specifically in hepatocytes in vivo. The data is a part of a study on the involvement of ceramide enzymatic machinery in card...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD025957 | Pride
Silencing Liver Mouse Proteome Ceramide synthase 2 
ProteomicsScoelicolor A3(2) - Whole organism, normlized TMT (Rioserasetal,molcellproteomics2018)
abundance based on normlized TMT, Interaction consistency score: 8.2, Coverage: 45
ORGANISM(S): 100226 
2018-00-00 | 3141927513 | PAXDB
ProteomicsCOMPARATIVE ANALYSIS OF THE PROTEOME OF KUPFFER CELLS AND MONOCYTES
Macrophage population in most mammalian organs consists of cells of different origin, with the exception of the central nervous system and the liver, where macrophages of monocytic origin are almost completely absent. The reasons for such distribution and the phenomenon of coexistence of the two sep...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD018586 | Pride
Kuppfer cells Macrophages Monocytes 
ProteomicsNeuroprotective properties of Mesenchymal Stromal Cell–Derived Extracellular Vesicles in Models of Acute Brain Pathology
Extracellular vesicles (EVs) of multipotent mesenchymal stromal cells (MSCs) in various studies have shown a wide range of cytoprotective effects, including neuroprotective ones. It is important to note that the therapeutic effect of EVs is observed regardless of the tissue from which MSCs were isol...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD027581 | Pride
Msc Extracellular vesicles Neuroprotection 
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