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ModelsRoy2019 - A vivid cytokines interaction model on psoriasis with the effect of impulse biologic therapy
This is a mathematical model describing keratinocyte proliferation dynamics as influenced by immune cells and cytokines within the context of psoriasis. The model also investigates the perfect dosing interval for therapeutic dosages of TNF-alpha inhibitors for the treatment of psoriasis.
2019-11-07 | MODEL1911070001 | BioModels
UnknownEmerging role of narrow band imaging in duodenum.
Not available
S-EPMC4639743 | biostudies-literature
UnknownChronic cholesterol depletion increases F-actin levels and induces cytoskeletal reorganization via a dual mechanism.
Not available
S-EPMC9096963 | biostudies-literature
ProteomicsGefitinib results in robust host-directed immunity against Salmonella infection through proteo-metabolomic reprogramming.
The rise of antibiotic-resistant strains of Salmonella has demand the development of alternative therapeutic strategies. Recent studies have shown that targeting host factors may provide an alternative approach for the treatment of intracellular pathogens. Host-directed therapy (HDT) modulates host ...
ORGANISM(S): Homo sapiens (Human) 
2021-03-26 | PXD024771 | Pride
Salmonella Proteo-metabolomic Dia Swath-ms Thp-1 
ProteomicsRUFY3 links Arl8b and JIP4-Dynein complex to regulate lysosome size and positioning
The whole-cell scale spatial organization of lysosomes is regulated by their bidirectional motility on microtubule tracks. Small GTP-binding (G) protein, Arl8b, stimulates the anterograde transport of lysosomes by recruiting adaptor protein SKIP (also known as PLEKHM2), which in turn couples the mic...
ORGANISM(S): Homo sapiens (Human) 
2022-03-23 | PXD027010 | Pride
Arl8b Lysosome Small gtpase Dynein Microtubule 
UnknownA molecular sensor for cholesterol in the human serotonin1A receptor.
Not available
S-EPMC8302130 | biostudies-literature
TranscriptomicsDetection of Cancer with Serum miRNAs on an Oligonucleotide Microarray
Micro RNAs (miRNAs) are a class of small, non-coding RNA species that play critical roles throughout cellular development and regulation. miRNA expression patterns taken from various tissue types often point to the cellular lineage of an individual tissue Arrays for serum miRNA analysis were constru...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-16512 | biostudies-arrayexpress
TranscriptomicsA 7-month inhalation toxicology study in C57BL/6 mice demonstrates reduced pulmonary inflammation and emphysema following smoking cessation or switching to e-vapor products.
Cigarette smoking causes serious diseases, including lung cancer, heart disease, and emphysema. While cessation remains the most effective approach to minimize smoking-related disease, alternative non-combustible tobacco-derived nicotine containing products may reduce disease risks among those unabl...
ORGANISM(S): Mus musculus 
2021-03-18 | E-MTAB-9597 | biostudies-arrayexpress
UnknownLeishmania donovani Internalizes into Host Cells via Caveolin-mediated Endocytosis.
Not available
S-EPMC6718660 | biostudies-literature
TranscriptomicsMycobacterium tuberculosis whiB4 mutant expression
Comparison of gene expression profile of the whiB4 mutant strain of Mycobacterium tuberculosis with the wild type Mycobacterium tuberculosis H37RV Mtb WhiB4 mutant mRNA was compared with the mRNA of wtMtb H37RV under aerobic conditons Aerbic conditions OD600 nm of 0.4, MtbWhiB4KO vs wtMtb, biologica...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2012-07-23 | E-GEOD-37840 | biostudies-arrayexpress
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