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ProteomicsProteomic analysis of small and large EVs from DKs8 cells
We used iTRAQ-quantitative proteomics analysis to identify protein cargos that may contribute to different functions of exosome-enriched small extracellular vesicles (EVs) and MV-enriched large EVs derived from a colorectral cancer cell line, DKs8.
ORGANISM(S): Homo sapiens (Human) 
2019-01-17 | PXD010840 | Pride
Exosomes Proteomics Extracellular vesicles Microvesicles Itraq 
ProteomicsMDA-MB-231 blebbisome proteomics
Cells secrete a large variety of extracellular vesicles (EVs) to engage in cell-to-cell and cell-to-environment intercellular communication. EVs are functionally involved in many physiological and pathological processes by interacting with cells that facilitate transfer of proteins, lipids and genet...
ORGANISM(S): Homo sapiens (Human) 
2025-01-05 | PXD059407 | Pride
Ectosomes Microvesicles Large evs Small evs Proteomics Blebbisomes Lc-ms/ms 
ProteomicsSurface proteome of large extracellular vesicles
The extracellular vesicle (EV) surface proteome (surfaceome) acts as a fundamental signalling gateway by bridging intra-and extracellular signalling networks, dictates EVs’ capacity to communicate and interact with its the/their environment, and is a source of potential disease biomarkers and thera...
ORGANISM(S): Homo sapiens (Human) 
2021-11-17 | PXD026658 | Pride
Proteomics Extracellular vesicles Large extracellular vesicles Interactome Surface 
TranscriptomicsRapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins
Background: Exosomes and extracellular vesicles (EVs) are increasingly recognized as important sources of biomarkers for disease study and diagnosis. Results: A synthetic peptide, Vn96, allows for capture of EVs from biological fluids using basic laboratory equipment. Conclusion: The Vn96-captured E...
ORGANISM(S): Homo sapiens 
2014-06-14 | E-GEOD-58464 | biostudies-arrayexpress
MetabolomicsIndustrial by-products as a novel circular source of biocompatible extracellular vesicles

Extracellular vesicles (EVs) constitute an intricate system of molecular exchange that has recently gained tremendous interest. However, sustainable sources of safe biological EVs remain scarce and elusive. In this study we explore and define the use of food industry byproducts (BP) as a circular...

2022-05-17 | MTBLS2801 | MetaboLights
TranscriptomicsOsteoblasts secrete miRNA-containing extracellular vesicles that enhance expansion of human umbilical cord blood cells
Osteolineage cells represent one of the critical bone marrow niche components that support maintenance of hematopoietic stem and progenitor cells (HSPCs). Recent studies demonstrate that extracellular vesicles (EVs) regulate stem cell development via horizontal transfer of bioactive cargo, including...
ORGANISM(S): Homo sapiens 
2016-10-05 | E-MTAB-4560 | biostudies-arrayexpress
GenomicsmiRNA expression data from HPC-EVs
miRNA expression data from HPC-EVs
PRJNA1030338 | ENA
ProteomicshTERT mesenchymal stem cells (MSCs), Stem cells EVs LC-MS/MS
As the economic challenges associated with vision impairment and ocular injuries continue to escalate, there exists an urgent need to explore innovative remedies for these conditions. Extracellular Vesicles (EVs), containing a diverse array of biological components such as nucleic acids, proteins, a...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD044629 | Pride
Stem cells Evs Lc-ms/ms 
ProteomicsTrypanosoma cruzi interaction with host tissues modulate the composition of large extracellular vesicles
Trypanosoma cruzi is the protozoan that causes Chagas disease, an endemic parasitosis in Latin America that has spread around the globe. Recently, a series of studies indicate that the gastrointestinal tract represents an important reservoir for T. cruzi in the chronic phase. It is also known that, ...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) Trypanosoma cruzi Dm28c Trypanosoma cruzi strain CL Brener 
2024-05-17 | PXD046906 | Pride
Mass spectrometry Tropism Microvesicles Extracellular vesicles Trypanosoma cruzi 
TranscriptomicsFluidigm Biomark 96.96 nanofluidic arrays for qRT-PCR of 93 miRNAs: salivary extracellular vesicles
Crude extracellular vesicles (EVs) from eight healthy volunteers were separated into 6 fractions based on their densities by using the iodixanol-based density gradient centrifugation method. To determine the distribution of miRNAs among these fractions, quantities of 93 miRNAs were quantified by the...
ORGANISM(S): Homo sapiens 
2016-08-01 | E-GEOD-78763 | biostudies-arrayexpress
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