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ProteomicsIdentification of PP2A-B55 targets in Drosophila uncovers regulation of Emerin during nuclear envelope reassembly
Entry into mitosis is triggered by mitotic kinases that phosphorylate multiple proteins to induce profound cellular changes including nuclear envelope breakdown, chromosome condensation and spindle assembly. Conversely, mitotic exit requires protein dephosphorylation as cells return to their interph...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-08-10 | PXD041032 | Pride
Otefin Pp2a Baf Lamin Nuclear envelope Mitotic exit Mitosis Emerin 
ProteomicsIdentification of PP2A-B55 targets in Drosophila uncovers regulation of Emerin during nuclear envelope reassembly
Entry into mitosis is triggered by mitotic kinases that phosphorylate multiple proteins to induce profound cellular changes including nuclear envelope breakdown, chromosome condensation and spindle assembly. Conversely, mitotic exit requires protein dephosphorylation as cells return to their interph...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-08-10 | PXD041030 | Pride
Otefin Pp2a Baf Lamin Nuclear envelope Mitotic exit Mitosis Emerin 
ProteomicsIdentification of PP2A-B55 targets in Drosophila uncovers regulation of Emerin during nuclear envelope reassembly
Entry into mitosis is triggered by mitotic kinases that phosphorylate multiple proteins to induce profound cellular changes including nuclear envelope breakdown, chromosome condensation and spindle assembly. Conversely, mitotic exit requires protein dephosphorylation as cells return to their interph...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-08-10 | PXD041091 | Pride
Otefin Pp2a Baf Lamin Nuclear envelope Mitotic exit Mitosis Emerin 
ProteomicsLC-MSMS of OVCAR-3 class I immunopeptidome
Endogenous retroelements (ERE) constitute about 42% of the human genome and have been implicated in common human diseases such as autoimmunity and cancer. Despite evidence that some EREs can be expressed at the RNA and protein levels in specific contexts, a systems-level evaluation of their expressi...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD018124 | Pride
Lc-msms Ovcar-3 Immunopeptidome Mhc class i 
ProteomicsLC-MSMS of the MHC-I immunopeptidome of human melanoma
While immune checkpoint blockade (ICB) therapy has significantly improved the outcome of metastatic melanoma and non-small cell lung cancer (NSCLC), most patients do not derive long-term benefits. Previous studies suggest that treatment failure is partly due to insufficient immune recognition of tum...
ORGANISM(S): Homo sapiens (Human) 
2025-02-19 | PXD043059 | Pride
Lc-msms Melanoma Immunopeptidome Mhc class i 
ProteomicsLC-MSMS of the MHC-I immunopeptidome of human NSCLC samples
While immune checkpoint blockade (ICB) therapy has significantly improved the outcome of metastatic melanoma and non-small cell lung cancer (NSCLC), most patients do not derive long-term benefits. Previous studies suggest that treatment failure is partly due to insufficient immune recognition of tum...
ORGANISM(S): Homo sapiens (Human) 
2025-02-19 | PXD043057 | Pride
Non-small cell lung cancer Lc-msms Immunopeptidome Mhc class i 
UnknownAdding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial.
Not available
S-EPMC7616360 | biostudies-literature
UnknownDuration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in the RADICALS-HD randomised trial.
Not available
S-EPMC7616389 | biostudies-literature
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