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Protein kinase R (PKR) is a key antiviral kinase activated by binding double-stranded RNA (dsRNA) produced during viral replication. Upon activation, PKR phosphorylates eIF2α, leading to the inhibition of translation and viral replication. However, many viruses have evolved mechanisms to counteract ...
ORGANISM(S): Homo sapiens (Human) 
2025-11-17 | PXD066206 | Pride
These data are from two wild-type HeLa clones (WT1, WT2) and two TBC1D20-null clones (5H2, 7H5), each analysed in triplicate.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD016233 | Pride
These data are from two wild-type RPE1 clones (WT11, WT20), a RAB18-null clone, a TBC1D20-null clone, a RAB3GAP1-null clone and a RAB3GAP2-null clone, each analysed in triplicate.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD016326 | Pride
Proximity labelling using transient expression of the same exogenous BioID2(Gly40Ser)-SEC22A construct in wild-type HeLa cells and in otherwise isogenic RAB3GAP1-, RAB3GAP2- and RAB18-null HeLa cell lines.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD016404 | Pride
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