Sort   by:  
 Page size 
ProteomicsPlasma Proteomic Changes of Atherosclerosis After Exercise in ApoE knockout Mice
Atherosclerosis is the preliminary cause of coronary artery disease, one of the diseases that ac-count for the largest number of fatal mortalities. Physical activity is an effective strategy to restrain atherosclerosis from deterioration. Evidence indicated that the changes of proteomic profile is h...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-04 | PXD030951 | Pride
Atherosclerosis  complement factor c5  exercise  proteomic changes  chemotaxis 
ProteomicsComparative O-GlcNAc Proteomic Analysis Reveals a Role of O-GlcNAcylated SAM68 in Lung Cancer Aggressiveness
O-GlcNAcylation is a reversible and dynamic post-translational protein modification catalyzed by O-GlcNAc transferase (OGT). Despite the reported association of O-GlcNAcylation with cancer metastasis, the O-GlcNAc proteome profile for cancer aggressiveness remains largely uncharac-terized. Here we r...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD029627 | Pride
Lung adenocarcinoma  o-glcnac transferase  o-glcnacylation  sam68 
ProteomicsResveratrol Suppresses Susceptibility of Ventricular Arrhythmia in Heart Failure Model
In a rabbit heart failure model, resveratrol treatment restored cardiac function, normalized calcium handling, and reduced ventricular arrhythmia by reversing ion channel downregulation, fibrosis, apoptosis, and inflammation. These findings highlight resveratrol’s cardioprotective potential as a the...
ORGANISM(S): Oryctolagus cuniculus (Rabbit) 
2026-01-12 | PXD069110 | Pride
Heart failure Calcium handling Ion channels Ventricular arrhythmia Optical mapping 
ProteomicsEffects of Caloric Restriction with Protein Supplementation on Plasma Protein Profiles in Middle-Aged Women with Metabolic Syndrome – A Preliminary Open Study
Clinical studies have demonstrated that higher protein intake based on caloric restriction (CR) alleviates metabolic abnormalities. However, no study has examined the effects of plasma protein profiles on caloric restriction with protein supplementation (CRPS) in metabolic syndrome (MetS). Therefore...
ORGANISM(S): Homo sapiens (Human) 
2019-11-13 | PXD012213 | Pride
Metabolic syndrome  caloric restriction  protein supplementation  plasma proteomics 
ProteomicsMaintenance of Neural Activities in Torpid Rhinolophus ferrumequinum Bats Revealed by 2D Gel-based Proteome Analysis
Bats are the only mammals capable of self-powered flying. Many bat species hibernate in winter. A reversible control of cerebral activities is critical for bats to accommodate a repeated torpor-arousal cycle during hibernation. Little is known about the molecular mechanism that regulates neuronal ac...
ORGANISM(S): Bos taurus (Bovine) Pan troglodytes (Chimpanzee) Rattus rattus (Black rat) Arabidopsis thaliana (Mouse-ear cress) Mesocricetus auratus (Golden hamster) Homo sapiens (Human) Mus musculus (Mouse) Sus scrofa domesticus (domestic pig) Rattus norvegicus (Rat) Equus caballus (Horse) 
2017-05-11 | PXD005158 | Pride
Gnao1 Hibernation Palmitoylation Bats Lc-ms/ms 
ProteomicsActivation of Akt, Nrf2, and NF-κB signal transduction pathways in the liver as a mechanism of survival for torpid Myotis ricketti Bats
Unfolded protein accumulation in the lumen of endoplasmic reticulum (ER) induced by cold exposure is termed UPRER. Some mammals hibernate to overcome cold winter. We investigated whether hibernating bats are under UPRER and activate Akt, Nrf2, and NF-κB signaling pathways that are critical for cell ...
ORGANISM(S): Myotis ricketti 
2020-11-17 | PXD016109 | Pride
Mitochondria Eif2 Akt Hibernation Upr And lc-ms/ms Nf-κb Bats Proteomics Liver 
ProteomicsStomatin modulates adipogenesis through ERK pathway and regulates fatty acid uptake and lipid droplet growth
Controlling fatty acid uptake, lipid production and storage, and metabolism of lipid droplets (LDs), is closely related to lipid homeostasis, adipocyte hypertrophy and obesity. We report here that stomatin, a major constituent of lipid rafts, participates in adipogenesis and adipocyte maturation by ...
ORGANISM(S): Mus musculus (Mouse) 
2022-07-05 | PXD031866 | Pride
Erk pathway Adipogenesis 3t3-l1 adipocyte-like cell 
UnknownLASSO and Bioinformatics Analysis in the Identification of Key Genes for Prognostic Genes of Gynecologic Cancer.
Not available
S-EPMC8617991 | biostudies-literature
UnknownPeripheral sensory neuron injury contributes to neuropathic pain in experimental autoimmune encephalomyelitis.
Not available
S-EPMC5299449 | biostudies-literature
UnknownPredicting the Risk of Total Hip Replacement by Using A Deep Learning Algorithm on Plain Pelvic Radiographs: Diagnostic Study.
Not available
S-EPMC10625092 | biostudies-literature
Sort   by:  
 Page size