Sort   by:  
 Page size 
ProteomicsTrifunctional lipid derivatives: PEs mi-tochondrial interactome
In this study, we employed chemically synthesized trifunctional lipid probes to identify putative protein partners that interact with lipids in HeLa cells. These probes incorporate three distinct chemical functionalities. First, a coumarin-based “caging” moiety is added to the lipid head group, whic...
ORGANISM(S): Homo sapiens (Human) 
2025-01-21 | PXD059960 | Pride
Phosphatidic-acid Trifunctional lipid Phospholipid Phosphatidylinositol Phosphatidylethanolamine Lipid interactome 
UnknownLipid- and protein-directed photosensitizer proximity labeling captures the cholesterol interactome.
Not available
S-EPMC11370482 | biostudies-literature
ProteomicsTurboID-based proximity labeling of ER-localized TMEM120A/B interactome in Oleic Acid-treated HEK293T cells
Raw mass spectrometry data (.d raw data from Bruker) supporting the study: "A conserved ER protein prevents lipotoxicity by stimulating the key enzyme in glycerolipid synthesis". This dataset contains LC-MS/MS raw files from a proximity labeling experiment (TurboID) designed to identify interacting ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD075982 | Pride
Proximity labeling Turboid Tag Lipid droplet 
TranscriptomicsCultured chicken embryonic hepatocytes (CEH) exposed to linear PFOS (L-PFOS) or technical-grade PFOS (T-PFOS)
Recently it was discovered that the perfluorooctane sulfonate (PFOS) detected in wildlife, such as fish-eating birds, had a greater proportion of linear PFOS (L-PFOS) than the manufactured technical product (T-PFOS), which contains linear and branched isomers. This suggests toxicological studies bas...
ORGANISM(S): Gallus gallus 
2011-10-28 | E-GEOD-33291 | biostudies-arrayexpress
ProteomicsEXPLORING THE INTERACTOME OF PML NUCLEAR SUBDOMAINS DURING FATTY ACID STRESS USING APEX2-MEDIATED PROXIMITY LABELING
When exposed to excess fatty acids, specific cell types produce nuclear lipid droplets (nLDs) that associate with promyelocytic leukemia (PML) protein to form Lipid Associated PML Structures (LAPS) that are enriched in lipid biosynthetic enzymes but deficient in canonical proteins associated with PM...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD053509 | Pride
Nuclear lipid droplet Promyelocytic leukemia Copii Proximity-dependent biotin identification Apex2 Lipid-associated pml structures 
ProteomicsComparison of the regenerative effect of microalgae Nannochloropsis oceanica and Chlorococcum amblystomatis lipid extracts on redox-dependent metabolic changes in human skin fibroblasts caused by UVA radiation. Proteomic study. (This research is funded by the National Science Center in Poland (Narodowe Centrum Nauki, NCN) within MINIATURA 8 registration no 2024/08/X/NZ7/00029)
Lipid extracts, specifically from marine microalgae Nannochloropsis oceanica (N.o.) and freshwater microalgae Chlorococcum amblystomatis (C.a.) in this research proposal, offer a great potential in the development of new pharmacotherapeutic applications against skin disease, accompanied by oxidative...
ORGANISM(S): Homo sapiens (Human) 
2026-05-06 | PXD078022 | Pride
Microalgae lipid extracts  oxidative stress: inflammation  human skin fibroblasts  proteomics  uva radiation  3d-cell cultures. 
UnknownExploring the ATG9A interactome uncovers interaction with VPS13A.
Not available
S-EPMC10911177 | biostudies-literature
ProteomicsPannexin 1 interactome in Rhabdomyosarcoma
We have recently reported the down-regulation of pannexin 1 (PANX1) levels in rhabdomyosarcoma (RMS) and that restoration of its expression inhibits the progression of embryonal (eRMS) and alveolar (aRMS) rhabdomyosarcoma in vitro and in vivo. While we have shown that this PANX1-mediated inhibition ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-30 | MSV000084867 | MassIVE
UnknownThe proximity interactome of PML isoforms I and II under fatty acid stress.
Not available
S-EPMC11891419 | biostudies-literature
UnknownMechanistic dissection of diabetic retinopathy using the protein-metabolite interactome.
Not available
S-EPMC7843730 | biostudies-literature
Sort   by:  
 Page size