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RNA-seq of C.elegans strain N2 (wt) with and without sfa-1 RNAi at adult day 3 and day 15, C. elegans strain DA1116 (eat-2(ad1116)) with and without sfa-1 RNAi at adult day 3, day 15, and day 27, C. elegans strain SS104 (glp-4(bn2)) with and without hrp-2 RNAi at adult day 1, and HeLa cells with and...
ORGANISM(S): Caenorhabditis elegans 
Neuronal mTORC1 inhibition promotes longevity without suppressing anabolic growth and reproduction in C. elegans
A SWATH-based worflow has been developed for C. elegans proteome profiling, including sample preparation, SWATH spectral library generation and downstream data treatment. The influences of several RNAi treatments (including mrps5, fzo1, drp1, eat3) on C. elegans total proteome were studied.
ORGANISM(S): Caenorhabditis elegans 
2020-04-03 | PXD009256 | Pride
Efficacy of longevity interventions in C. elegans is determined by early life activity of RNA splicing factors
Efficacy of longevity interventions in C. elegans is determined by early life activity of RNA splicing factors II
The CRTC-1 transcriptional domain is required for COMPASS complex mediated longevity in C. elegans
Twenty years since publication of the Plasmodium falciparum and P. berghei genomes one-third of their protein-coding genes lack functional annotation. In the absence of sequence and structural homology, protein-protein interactions can facilitate functional prediction of such orphan genes by mapping...
ORGANISM(S): Plasmodium 
2022-08-21 | PXD034491 | Pride
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