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TranscriptomicsIncreased antigen cross-presentation but impaired cross-priming after activation of PPARγ
Increased antigen cross-presentation but impaired cross-priming after activation of PPARγ is mediated by up-regulation of B7H1 Dendritic cells (DCs) are able to take up exogenous antigens and present antigen-derived peptides on MHC class I molecules, a process termed cross-presentation. The mannose...
ORGANISM(S): Mus musculus 
2010-05-08 | E-GEOD-15616 | biostudies-arrayexpress
ProteomicsImpact of asialoglycoprotein receptor and mannose receptor deficiency on murine plasma N-glycome profiles
The asialoglycoprotein receptor (ASGPR) and the mannose receptor 1 (MRC1) are C-type lectins that identify and remove glycoproteins from circulation. ASGPR recognizes terminal galactose and N-acetylgalactosamine, whereas MRC1 recognizes terminal mannose, fucose, and N-acetylglucosamine. The effects ...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD042269 | Pride
Asialoglycoprotein receptor Glycomics Clearance Proteomics Mannose receptor 
TranscriptomicsTranscription profiling of S. cerevisiae phosphomannose isomerase PMI40 deletion strain grown on mannose
YEAST STRAIN:,A genetically modified Saccharomyces cerevisiae yeast strain with PMI40 knockout (MATa URA3 TRP1 LEU2 his3- 1 MAL2-8C SUC2 PMI40::HIS3). The parent strain was CEN.PK113-7A (MATa URA3 TRP1 LEU2 his3- 1 MAL2-8C SUC2) obtained from Euroscarf (9).,CULTIVATION MEDIUM:,The mineral medium use...
ORGANISM(S): Saccharomyces cerevisiae 
2007-07-08 | E-GEOD-1938 | biostudies-arrayexpress
ProteomicsMannose receptor (CD206) N-glycosylation
To explore the influence of glycosylation on mannose receptor (MR) binding to glycan ligands, we used the mouse CTLD4-7, fused to the Fc-portion of human IgG (MR-Fc) and human full-length MR. A detailed N- and O-glycopeptide analysis was performed using tryptic glycopeptides. In addition the samples...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-03-11 | PXD034781 | Pride
Glycosylation O-linked glycosylation Mass spectrometry Glycoproteomics Glycan microarray Mannose receptor Glycobiology N-linked glycosylation Lectin 
TranscriptomicsRNA-seq of AML cells with MPI KO and FLT3 tyrosine kinase inhibition
Molm13 AML cell line both control and MPI KO, treated with AC220 (quizartinib) and mannose at 24 and 72 hours after drug treatment. 2 reads and 2 repeats for each condition, 2 timepoints, 48 total files.
ORGANISM(S): Homo sapiens 
2023-02-27 | E-MTAB-11750 | biostudies-arrayexpress
ProteomicsMannose Receptor glycoprotein ligands in A549 cells
The macrophage mannose receptor (CD206, MR) is an endocytic lectin receptor which plays an important role in homeostasis and innate immunity. The MR contains C-type lectin domains (CTLD) whose specificity for endogenous glycans and glycoprotein ligands have not been well studied. To gain more insig...
ORGANISM(S): Homo sapiens (Human) 
2022-06-21 | PXD022546 | Pride
Glycoproteomics Mannose receptor Lc-ms A549 
TranscriptomicsStudying the phosphosugar stress in Bacillus subtilis using differential gene expression analysis of wildtype and manA deletion mutant grown on LB mannose medium
Bacillus subtilis has different response systems to cope with external and internal stressors. In this study, we investigated the effect of phosphosugar stress caused by accumulation of phosphosugars in B. subtilis. To do so, manA, the encoding gene of mannose-6-phosphate isomerase, was deleted in B...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2019-06-06 | E-MTAB-7262 | biostudies-arrayexpress
TranscriptomicsLY75 modulates epithelial to mesenchymal transition and metastatic potential of ovarian cancer cells
Epithelial ovarian cancer (EOC) accounts for 4% of all cancers in women and is the leading cause of death from gynecologic malignancies. It is well established that cancer invasion and metastasis still represent the major causes of the failure of cancer treatment. Previously, we identified the manno...
ORGANISM(S): Homo sapiens 
2016-04-01 | E-GEOD-74711 | biostudies-arrayexpress
MetabolomicsErythrocyte adenosine A2B receptor-mediated AMPK activation: Counteracting CKD by promoting oxygen delivery
Not available
ORGANISM(S): Mus musculus 
ST001153 | MetabolomicsWorkbench
ProteomicsMurine bronco alveolar lavage fluid from wild type and mannose receptor knock out mice, unchallenged and LPS challenged
A comparative analysis of the protein content in bronco alveolar lavage fluid from wild type and mannose receptor knock-out littermate mice. This includes both an unchallenged mice and mice subjected to intratracheal LPS instillation to induce injury and inflammation.
ORGANISM(S): Mus musculus (Mouse) 
2024-04-17 | PXD049201 | Pride
Broncho alveolar lavage fluid Lung Tmt 10plex Lps treatment Lc-ms3 Murine Mannose receptor 
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