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MetabolomicsLarge-Scale Plasma Analysis Revealed New Mechanisms and Molecules Associated with the Host Response to SARS-CoV-2
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to nearly every continent, registering over 1,250,000 deaths worldwide. The effects of SARS-CoV-2 on host targets remains largely limited, hampering our understanding of Coronavirus Disease 2019 (COVID-19) pathogenesis...
2021-11-04 | MTBLS1866 | MetaboLights
ProteomicsStructural and functional differentiation of the light-harvesting protein Lhcb4 during land plant diversification
About 475 million years ago plants originated from an ancestral green alga and evolved first as non-vascular and later as vascular plants, becoming the primary producers of biomass on lands. During that time, the light harvesting complex II (LHCII), responsible for sunlight absorption and excitation...
ORGANISM(S): Pisum sativum (Garden pea) 
2019-03-25 | PXD011213 | Pride
Proteomics Light acclimation Swath Psii Land plants evolution Label-free Lhcii Light harvesting 
ProteomicsExploring the Wound Healing, Anti-Inflammatory, Anti-Pathogens and Proteomic Effects of Lactic Acid Bacteria on Keratinocytes
The topical application of lactic acid bacteria (LAB) is recognized as a useful approach to improve skin health. This work aims to characterize by a multidisciplinary approach, the wound healing, anti-inflammatory, anti-pathogens and proteomic effects of six LAB lysates, belonging to the genus Lacto...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018088 | Pride
Keratinocytes  lactic acid bacteria  proteomics  anti-inflammatory  wound healing 
UnknownGold Nanoparticles as a Possible Tool to Untangle Some Structural Features of the Gluten Network.
Not available
S-EPMC12691966 | biostudies-literature
ProteomicsTrichostatin A alters cytoskeleton and energy metabolism of pancreatic adenocarcinoma cells: an in depth proteomic study.
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal of all human cancers with a high mortality rate. Resistance to conventional treatments and chemotherapeutics is a typical feature of PDAC. To investigate the causes of drug resistance it is essential to deeply investigate the mechanis...
ORGANISM(S): Homo sapiens (Human) 
2017-11-08 | PXD007801 | Pride
Trichostatin a Metabolism Pancreatic cancer Cytoskeleton Shotgun proteomics 2-deoxy-d-glucose 
ProteomicsInvestigation of the protein profile of silkworm (Bombyx mori) pupae reared on a well-calibrated artificial diet compared to mulberry leaf diet
Background. Silkworm pupae (SWP) is the main by-product of the sericulture industry with an interesting nutritional profile, especially in terms of proteins. In consideration of its possible use as a food or food ingredient in Western countries, a comparative proteomic experiment has been performed ...
ORGANISM(S): Bombyx mori (Silk moth) 
2019-06-03 | PXD012869 | Pride
Proteomics Bombyx mori Lc-ms/ms 
ProteomicsCan half-marathon affect overall health? The yin-yang of sport
Physical activity improves overall health and counteracts metabolic pathologies. Adipose tissue and bone are important key targets of exercise; the prevalence of diseases associated with suboptimal physical activity levels has increased in recent times as a result of lifestyle changes. Mesenchymal s...
ORGANISM(S): Homo sapiens (Human) 
2017-09-25 | PXD006704 | Pride
Pparg Half marathon Runx2 Plasma proteomics 
ProteomicsThylakoid membrane proteome remodelling in response to variation in plant growth irradiance
Plant thylakoid membranes contain hundreds of proteins closely interplaying to cope with ever-changing environmental conditions. We investigated how P. sativum (pea) grown at different irradiances optimizes light-use efficiency through the differential accumulation of thylakoid proteins. Thylakoid m...
ORGANISM(S): Pisum sativum (Garden pea) 
2018-10-02 | PXD009448 | Pride
Thylakoid membrane Swath analysis Photosynthesis Quantitative proteomics Light acclimation 
ProteomicsRUNX2 stimulates neoangiogenesis through the RUNT domain in melanoma
Transcription factors, by acting on gene expression can affect molecular pathways and can thereby induce malignant transformation. Among the transcription factors involved in cellular transformation, we recently highlighted the role of RUNX2 in melanoma cell migration and proliferation. In the prese...
ORGANISM(S): Homo sapiens (Human) 
2019-11-13 | PXD012096 | Pride
Runx2 Neoangiogenesis Melanoma Proteomics 
ProteomicsPlasma Proteome profiles of stable CAD patients stratified according to total Apo CIII levels
Apolipoprotein C-III was recently acknowledged as a prognostic marker for cardiovascular risk. High levels of Apo-CIII strongly correlate with hypertriglyceridemia and are associated with atherosclerosis and coronary heart disease (CAD). Aim of the present research was to study the plasma proteome p...
ORGANISM(S): Homo sapiens (Human) 
2018-07-05 | PXD005973 | Pride
Apolipoproteins Coronary artery disease Cardiovascular disease Apo c-iii Plasma proteomics 
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