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ProteomicsQuantitative proteomic analysis of fresh-frozen human breast tissue and tumor samples using microLC-SWATH-MS
Future improvements in the field of breast cancer prevention, diagnosis and treatment require deeper knowledge and better understanding of the molecular processes and signaling pathways that lead to the transformation of normal cells to cancer ones and the disease progression. Quantitative proteome ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD008408 | Pride
Breast tissue Fresh frozen Breast tumor Microlc Swath-ms Quantitative proteomics 
UnknownAffinity depletion versus relative protein enrichment: a side-by-side comparison of two major strategies for increasing human cerebrospinal fluid proteome coverage.
Not available
S-EPMC6390343 | biostudies-literature
UnknownA systematic analysis of eluted fraction of plasma post immunoaffinity depletion: implications in biomarker discovery.
Not available
S-EPMC3168506 | biostudies-literature
ProteomicsHuman serum samples - Acute and chronic blood serum proteome changes in patients with methanol poisoning
We carried out a prospective, longitudinal, single-center, observational cohort study of patients with confirmed acute methanol poisoning that were treated in hospitals during a mass methanol poisoning outbreak in the Czech Republic in 2012. Venous blood for proteomic analysis was obtained from 24 p...
ORGANISM(S): Homo sapiens (Human) 
2022-12-12 | PXD035726 | Pride
Lc-ms/ms Human Acute poisoning Serum Methanol 
UnknownAffinity Capture Enrichment versus Affinity Depletion: A Comparison of Strategies for Increasing Coverage of Low-Abundant Human Plasma Proteins.
Not available
S-EPMC7460666 | biostudies-literature
ProteomicsCharacterization of human plasma depletome from patients with schizophrenia
The proteome of blood plasma is an interesting source of biomarkers and a potential way to improve treatment outcomes in psychiatric disorders. But its wide dynamic concentration range makes reducing its complexity necessary. Thus, in proteomic studies, a few of the most abundant proteins are deplet...
ORGANISM(S): Homo sapiens (Human) 
2019-10-23 | PXD010273 | Pride
Depletion Depletome High-definition mse Proteomics Plasma 
ProteomicsHUMAN BLOOD SERUM PROTEOME CHANGES AFTER 6 HOURS OF SLEEP DEPRIVATION AT NIGHT
The aim of this study was to discover significantly changed proteins in human blood serum as a result of 6 h sleep loss at night. Eight females were reqruited. . Peripheral venous whole blood sampling was performed at 04:00, after 6 h of sleep and after 6 h of sleep deprivation (SD). Serum from each...
ORGANISM(S): Homo sapiens (Human) 
2023-09-26 | PXD021004 | Pride
Human blood serum Proteomics Sleep deprivation Cellular pathological associations Stress and cancer 
ProteomicsThe low abundance plasma proteome reveals changes associ-ated with breast implant capsular contracture
Capsular contracture (CC) is one of the most common post-operative complication associated with breast-implant associated infections. The mechanisms that lead to CC remain poorly understood. Plasma is an ideal biospecimen for early proteomics biomarker discovery. However, as higher-abundant proteins...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD044649 | Pride
Proteomics Tmt Breast implants Capsular contracture Human plasma 
ProteomicsProteomic analysis of human follicular fluid in poor ovarian responders during in vitro fertilization
Poor ovarian response (POR) observed in controlled ovarian stimulation (COS) is often observed during in vitro fertilization and embryo transfer (IVF-ET) cycles and is a major problem. A POR has been found to be related to several factors, including advanced age, high body mass index, and history of...
ORGANISM(S): Homo sapiens (Human) 
2018-07-05 | PXD005436 | Pride
Multiple reaction monitoring Follicular fluid Biomarker Proteomics Poor ovarian response 
ProteomicsThe Nodding Syndrome Cerebrospinal Fluid Proteome: A Lens into Neurodevelopmental Failure
Nodding Syndrome (NS), a pediatric epileptic encephalopathy of East Africa, has long defied etiological classification. Here, we report high-resolution untargeted proteomics of cerebrospinal fluid from Ugandan NS patients and controls that reveals widespread disruption across immune, proteostatic, s...
ORGANISM(S): Homo sapiens (Human) 
2026-01-20 | PXD068754 | Pride
Epilepsy Mars-14 depletion Sps-ms3 Cerebrospinal fluid (csf) Mass spectrometry Mia Biotoxins Tauopathy Neurodevelopment Tmtpro Nodding syndrome Mecp2 Isobaric labeling quantitative proteomics 
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