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MetabolomicsHeadspace volatile organic compounds from bacteria implicated in ventilator-associated pneumonia analysed by TD-GC/MS
Ventilator-associated pneumonia (VAP) is a healthcare-acquired infection arising from the invasion of the lower respiratory tract by opportunistic pathogens in ventilated patients. The current method of diagnosis requires the culture of an airway sample such as bronchoalveolar lavage, which is invas...
2018-08-08 | MTBLS497 | MetaboLights
UnknownGene expression polymorphism underpins evasion of host immunity in an asexual lineage of the Irish potato famine pathogen.
Not available
S-EPMC6032779 | biostudies-literature
ProteomicsElucidation of the inflammatory and neuroprotective molecular network of TNFalpha in neurons related to Alzheimer´s disease
Neuroinflammation is a hallmark of various neurological diseases such as Alzheimer’s disease. The aim of the study was to elucidate the dose-dependent in vitro molecular mechanism of TNFα in neurons related to neuroprotection and -degeneration. We performed a quantitative proteomics and phospho-prot...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2017-08-08 | PXD005675 | Pride
Neuroinflammation Creb Phosphoproteomics Alzheimer´s disease Mtor Tnfα 
TranscriptomicsNotch targets in KC Drosophila cells
To identify genes upregulated in response to Notch signalling in KC cells. Keywords: Expression analysis at a single timepoint (30' after Notch activation) KC cells were obtained from Dr Martin Zeidler. Control versus Notch activated KC cells: mRNA was extracted from KC cells incubated in the absenc...
ORGANISM(S): Drosophila melanogaster 
2010-06-23 | E-GEOD-9965 | biostudies-arrayexpress
ProteomicsAn integrated omics approach reveals synaptic plasticity changes in an APP/PS1 Alzheimer´s mouse model
Synaptic dysfunction occurs early in Alzheimer´s disease. However, efforts to protect against these detriments have not been possible due to the inadequate understanding of synaptic signalling pathways involved in the neuropathological disease process. The aim of this study was to elucidate the mole...
ORGANISM(S): Mus musculus (Mouse) 
2016-05-11 | PXD003312 | Pride
Cortex Synapse Neuroinflammation Tau protein Proteomics Hippocampus Mirna Amyloid Olfactory bulb Dendritic spine Brainstem 
TranscriptomicsHalobacterium salinarum NRC-1 growth curve, tiling arrays
Experimentally mapped transcriptome structure of H. salinarum NRC-1 by hybridizing total RNA (including RNA species <200 nt) to genome-wide high-density tiling arrays (60 mer probes with 40 nt overlap between contiguous probes). H. salinarum NRC-1 presents a number of interesting switches in metabol...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-17 | E-GEOD-12923 | biostudies-arrayexpress
MetabolomicsThe Impact of Ethnicity and Intra-Pancreatic Fat on the Postprandial Metabolome Response to Whey Protein in Overweight Asian Chinese and European Caucasian Women with Prediabetes
The 'Thin on the Outside Fat on the Inside' TOFI_Asia study found Asian Chinese to be more susceptible to Type 2 Diabetes (T2D) compared to European Caucasians matched for gender and body mass index (BMI). This was influenced by degree of visceral adipose deposition and ectopic fat accumulation in k...
2022-10-12 | MTBLS5568 | MetaboLights
TranscriptomicsHalobacterium salinarum NRC-1 growth curve
Halobacterium salinarum NRC-1 was grown in CM media, at 37oC in a waterbath with agitation of 125 rpm under constant light. Analysis of transcriptional changes during growth, in addition to mapping of transcriptome structure under the same conditions, provided interesting insights about regulatory l...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-17 | E-GEOD-12977 | biostudies-arrayexpress
UnknownRituximab extended schedule or re-treatment trial for low-tumor burden follicular lymphoma: eastern cooperative oncology group protocol e4402.
Not available
S-EPMC4171355 | biostudies-literature
TranscriptomicsHalobacterium salinarum NRC-1 conditional ChIP-chip for transcription initiation factor IIB 4 (TFBd)
Conditional ChIP-chip for TFBd at different growth stages. cmyc-tagged TFBd was immunoprecipitated at different growth stages (early log, stationary and late stationary phases) and hybridized to microarrays.
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-16 | E-GEOD-13108 | biostudies-arrayexpress
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