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ProteomicsBiochemical Pathways Triggered by Antipsychotics in Human Oligodendrocytes: Potential of Discovering New Treatment Targets
Schizophrenia is a psychiatric disorder that affects more than 21 million people worldwide. It is an incurable disorder and the primary means of managing symptoms is through administration of pharmacological treatments, which consist heavily of antipsychotics. First-generation antipsychotics have th...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD008892 | Pride
Proteomics Quetiapine Mechanism of action Haloperidol Schizophrenia Chlorpromazine Risperidone Biomarkers 
ProteomicsHuman MNC proteome - Proteome profiling of peripheral mononuclear cells from human blood
Proteome characterization of mononuclear cells extracted from human blood - Dataset 3
ORGANISM(S): Homo sapiens (Human) 
2013-01-03 | PRD000732 | Pride
ProteomicsProteome analysis of the MO3.13 cell line from human oligodendrocytes
MO3.13 is an immortal human-human hybrid cell line that express phenotypic characteristics of primary oligodendrocytes. It was created by fusing a 6-thioguanine-resistant mutant of the human rhabdomyosarcoma RD (cancer of skeletal muscle) with adult human oligodendrocytes by a lectin-enhanced polyet...
ORGANISM(S): Homo sapiens (Human) 
2013-10-09 | PXD000263 | Pride
Human  oligodendrocytes  proteome  c-hpp 
ProteomicsExploring the proteomes of the human cerebellum and visual cortex using shotgun mass spectrometry-data independent analyses
Not available
ORGANISM(S): Homo sapiens (Human) 
2012-04-04 | PRD000523 | Pride
ProteomicsProteome of the Human Corpus Callosum
Characterization of the human Anterior Temporal Lobe and Corpus Callosum: C-HPP
ORGANISM(S): Homo sapiens (Human) 
2014-06-05 | PXD000547 | Pride
Brain  corpus callosum  human proteome project  chromosome-based hpp 
ProteomicsProteome analyses of the human anterior temporal lobe
Characterization of the human Anterior Temporal Lobe and Corpus Callosum: C-HPP
ORGANISM(S): Homo sapiens (Human) 
2014-06-05 | PXD000548 | Pride
Brain  anterior temporal lobe  human proteome project  chromosome-based hpp 
ProteomicsProteome of the Human Corpus Callosum
Characterization of the human Anterior Temporal Lobe and Corpus Callosum: C-HPP
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-10 | MSV000083947 | MassIVE
ProteomicsProteome analyses of the human anterior temporal lobe
Characterization of the human Anterior Temporal Lobe and Corpus Callosum: C-HPP
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-16 | MSV000079590 | MassIVE
ProteomicsPlasma proteomic signature of major depressive episode in the elderly
Depression is a complex and multifactorial disease, affecting about 6.5% of the elderly population in what is referred to as late-life depression (LLD). Despite its public health relevance, there is still limited information about the molecular mechanisms of LLD. We analyzed the blood plasma of 50 o...
ORGANISM(S): Homo sapiens (Human) 
2023-03-07 | PXD034030 | Pride
Late-life depression  proteomics  aging  senescence 
ProteomicsInvestigating the Succinylome and Malonylome of Schizophrenia
The succinylome and malonylome of human oligodendrocyte precursors (MO3.13 line) and postmortem brain tissue (whole lysates and mitochondrial enrichments) were studied with shotgun mass spectrometry. The goal was to determine what changes in oligodendrocytes are induced with the addition of the NMDA...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD014188 | Pride
Schizophrenia Malonylation Succinylation Mk-801 Antipsychotics 
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