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ProteomicsThermal proteome profiling of Escherichia coli mutants
We performed two dimensional thermal proteome profiling (2D-TPP) in Escherichia coli mutants to measure changes in abundance and thermal stability.
ORGANISM(S): Escherichia coli 
2020-09-11 | PXD016589 | Pride
Escherichia coli Genetic perturbation Mutants Thermal proteome profiling 
ProteomicsFlotillin effects on heat shock in Staphylococcus aureus
We measured the impact of flotillin on the solubility of proteins after heat shock in Staphylococcus aureus, by measuring the effects of a knockout mutant.
ORGANISM(S): Staphylococcus aureus 
2024-06-10 | PXD041057 | Pride
Flotillin Heat shock Staphylococcus aureus Floa 
ProteomicsThermal proteome profiling of Salmonella enterica infection
We performed two dimensional thermal proteome profiling (2D-TPP) of the infection time course of Salmonella enterica.
ORGANISM(S): Salmonella enterica subsp. enterica str. xld 
2024-08-08 | PXD043344 | Pride
Salmonella Thermal proteome profiling Infection 
ProteomicsSecretome of Staphylococcus aureus under drug treatment
We measured the secreted protein fraction of Staphylococcus aureus exposed to drugs.
ORGANISM(S): Staphylococcus aureus 
2026-04-21 | PXD055903 | Pride
Drug Staphylococcus aureus Secretome 
ProteomicsThermal proteome profiling of caffeine in E. coli
We performed thermal proteome profiling of caffeine in WT and the rob deletion mutant of Escherichia coli.
ORGANISM(S): Escherichia coli 
2025-06-23 | PXD062960 | Pride
Thermal proteome profiling Escherichia coli Rob Tpp Caffeine 
ProteomicsLSD1 knockout effects on proteome
We measured the impact of deleting LSD1 on the proteome of Mus musculus.
ORGANISM(S): Mus musculus (Mouse) 
2024-07-17 | PXD042495 | Pride
Knockout Lsd1 Rescue Mouse 
ProteomicsMacrolide drug interactions in Bacteroidaceae
We profiled the proteome of Phocaeicola vulgatus and Bacteroides uniformis when exposed to dicumarol, benzobromarone and tolfenamic acid (and in combination with erythromin).
ORGANISM(S): Phocaeicola vulgatus Bacteroides uniformis 
2025-11-28 | PXD066285 | Pride
Erythromycin Dicumarol Macrolide Benzbromarone Bacteroides Tolfenamic acid 
ProteomicsEffects of gene knockout on Shigella proteome
We measured the impact of multiple genes on the proteome of Shigella.
ORGANISM(S): Shigella flexneri 5b 
2025-03-07 | PXD046629 | Pride
Knockout Shigella 
ProteomicsThermal proteome profiling of phosphorylated proteoforms
We combined thermal proteome profiling (TPP) with phosphopeptide enrichment to study the thermostability of phosphorylated proteoforms.
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD015993 | Pride
Phosphopeptides Meltome Phosphoproteomics Thermal proteome profiling 
ProteomicsThermal proteome profiling in Escherichia coli
We adapted thermal proteome profiling (TPP) to study the thermostability of Escherichia coli proteins in vivo. We monitored the E. coli meltome and proteome at different growth phases, in a tolC knock-out mutant and after drug treatment.
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2018-07-09 | PXD009495 | Pride
Target engagement Escherichia coli Drugs Growth phase Meltome Thermal proteome profiling 
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