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MetabolomicsIntegrating Blood Microsampling Devices with CE-MS for Untargeted Analysis of Polar Metabolomics

Capillary electrophoresis–mass spectrometry (CE-MS) offers considerable advantages for polar compound metabolomics analysis, including simple workflows, fast method development, and suitability for small sample volumes. Blood microsampling (BμS) techniques (such as dried blood spots, quantitative...

2026-01-13 | MTBLS13090 | MetaboLights
MetabolomicsAn LC-MS untargeted metabolomic comparison between three blood microsampling devices, whole blood, and plasma

Blood microsampling (BµS) devices collect less than 100 µL of blood, offering a less invasive and more cost-effective alternative to venipuncture. However, its metabolomic comparability to conventional samples remains unclear, and standardized BµS metabolomic workflows are lacking. This study com...

2026-06-01 | MTBLS10740 | MetaboLights
MetabolomicsDeep insights into microsampling technologies for global lipidomic profiling of human whole blood using high-throughput LC-MS

In recent years, blood microsampling (BμS) technologies have gained popularity, as they offer simplicity, minimal invasiveness, and suitability for remote sample collection. In this study, the aim was to explore the potential of three BμS devices for reliable untargeted lipidomic profiling using ...

2025-09-30 | MTBLS10722 | MetaboLights
GenomicsMicrosampling transcriptomics
A fast and cost-effective microsampling protocol incorporating reduced animal usage for time-series transcriptomics in rodent malaria parasites
PRJEB27301 | ENA
TranscriptomicsSCREENING STUDY TO IDENTIFY DIAGNOSTIC MARKERS FOR LUNG CANCER IN ENDOBRONCHIAL LINING FLUID
We investigated whether biomarker analysis in endobronchial epithelial lining fluid (ELF) collected by bronchoscopic microsampling may be useful for a definitive preoperative diagnosis. Therefore we compared ELF samples close to nodule and from the contralateral site from patients with malignant or ...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-27489 | biostudies-arrayexpress
TranscriptomicsVALIDATION STUDY TO VERIFY DIAGNOSTIC MARKERS FOR LUNG CANCER IN ENDOBRONCHIAL LINING FLUID
We investigated whether biomarker analysis in endobronchial epithelial lining fluid (ELF) collected by bronchoscopic microsampling may be useful for a definitive preoperative diagnosis. Therefore we compared ELF samples close to nodule and from the contralateral site from patients with malignant or ...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-27553 | biostudies-arrayexpress
UnknownMicrosampling in toxicology studies - maximising the scientific, business and 3Rs advantages.
Not available
S-EPMC11957253 | biostudies-literature
UnknownThe influence of serial 50 μL microsampling on rats administered azathioprine, the immunosuppressive drug.
Not available
S-EPMC10008918 | biostudies-literature
ProteomicsHuman whole blood processed with VAMS device
This project tested the use of a volumemetric absorptive microsampling device as a substrate to prepare whole blood for proteomic analysis by LC-MS. We demonstrated that VAMS are a useful substrate to trap proteins from blood, wash them to reduce highly abundant protein species which enabled single ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-21 | PXD028605 | Pride
Lc-ms Plasma Blood Microsampling Vams Human 
UnknownVolumetric absorptive microsampling for lumateperone analysis: method validation and stability evaluation.
Not available
S-EPMC12783156 | biostudies-literature
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