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MD-224 is a PROTAC that induces degradation of the human protein MDM2. However, we have found that it also induces degradation of a subset of nuclear receptors. DIA was performed to assess the overall specificity of MD-224 in 293T cells and the colorectal cancer cell line SNU-C4.
ORGANISM(S): Homo sapiens (Human) 
2025-09-18 | PXD066110 | Pride
Pancreatic cancer remains one of the most lethal of malignancies and a major health burden. We performed whole genome sequencing and CNV analysis of 100 pancreatic ductal adenocarcinomas. Chromosomal rearrangements leading to gene disruption were frequent, affecting genes known to be important in pa...
ORGANISM(S): Homo sapiens 
Analysis .bam files from HiSeq sequencing of Australian ICGC PDAC study samples, submitted 20130826
Sequencing data for Australian Pancreatic Cancer study submitted 20130102
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