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UnknownContrasting Patterns in the Evolution of Vertebrate MLX Interacting Protein (MLXIP) and MLX Interacting Protein-Like (MLXIPL) Genes.
Not available
S-EPMC4766361 | biostudies-literature
UnknownPRMT1 promotes the proliferation and metastasis of gastric cancer cells by recruiting MLXIP for the transcriptional activation of the β-catenin pathway.
Not available
S-EPMC10404965 | biostudies-literature
UnknownGenetic polymorphisms of <i>LMX1B</i> and <i>MLXIP</i> are associated with hip osteoarthritis in the Chinese population.
Not available
S-EPMC11404616 | biostudies-literature
ProteomicsSystematic genome perturbation reveals coordination of lipid droplets and metabolic gene regulation
Lipid droplets (LDs) store lipids for metabolic eneergy and are central to cellular lipid homeostasis. The mechanisms coordinating lipid storage in LDs with cellular metabolism are unclear but relevant to obesity-related diseases. Here we utilized genome-wide screening to identify genes that modulat...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD012640 | Pride
Metabolism Chrebp Mlx Mondoa Mondob Transcription facot Mlxipl Lipid droplets Glucose Mlxip 
TranscriptomicsSystematic genome perturbation reveals coordination of lipid droplets and metabolic gene regulation
Lipid droplets (LDs) store lipids for metabolic energy and are central to cellular lipid homeostasis. The mechanisms coordinating lipid storage in LDs with cellular metabolism are unclear but relevant to obesity-related diseases. Here we utilized genome-wide screening to identify genes that modulate...
ORGANISM(S): Homo sapiens 
2020-01-01 | GSE126002 | GEO
UnknownGenome-wide association study identifies novel type II diabetes risk loci in Jordan subpopulations.
Not available
S-EPMC5563445 | biostudies-literature
TranscriptomicsmiR-221 is required for endothelial tip cell behaviors during vascular development
Through deep sequencing and functional screening in zebrafish, we find that miR-221 is essential for angiogenesis. miR-221 knockdown phenocopied defects associated with loss of the tip cell-expressed Flt4 receptor. Furthermore, miR-221 was required for tip cell proliferation and migration, as well ...
ORGANISM(S): Danio rerio 
2012-02-28 | E-GEOD-35078 | biostudies-arrayexpress
TranscriptomicsmiR-223 Bone Marrow Derived Eosinophils
Gene expression profiling of bone marrow derived eosinophils from miR-223 wildtype or miR-223 deficient mice
ORGANISM(S): Mus musculus 
2012-08-25 | E-MEXP-3350 | biostudies-arrayexpress
GenomicsMondoA Drives Malignancy in B-ALL through Enhanced Adaptation to Metabolic Stress [ChIP-seq]
MondoA (also known as MLXIP), a member of the MYC interactome, has been described as an example of a metabolic sensor. By assessing patient data sets we found that MondoA overexpression is associated with a worse survival in pediatric common acute lymphoblastic leukemia (B-ALL). Using CRISPR/Cas9 an...
ORGANISM(S): Homo sapiens 
2021-04-04 | GSE168864 | GEO
TranscriptomicsMondoA Drives Malignancy in B-ALL through Enhanced Adaptation to Metabolic Stress [array]
MondoA (also known as MLXIP), a member of the MYC interactome, has been described as an example of a metabolic sensor. By assessing patient data sets we found that MondoA overexpression is associated with a worse survival in pediatric common acute lymphoblastic leukemia (B-ALL). Using CRISPR/Cas9 an...
ORGANISM(S): Homo sapiens 
2021-04-04 | GSE168865 | GEO
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