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Peroxisomes are primarily metabolic organelles with important functions in lipid metabolism, such as fatty acid oxidation and ether phospholipid synthesis (e.g. plasmalogens). Certain viruses, such as human cytomegalovirus (HCMV), hijack organelle functions to facilitate their replication and spread...
2018-10-22 | MTBLS652 | MetaboLights
Emerging evidence points to protein acetylation as a nexus at the interface of virus-host interactions. However, global protein acetylation is understudied during infection, and the temporal control and function of acetylation in the context of infection remains poorly understood. Here, we present t...
ORGANISM(S): Homo sapiens (Human) 
2018-11-21 | PXD009839 | Pride
Emerging evidence points to post translational modification (PTM) of nuclear lamins as a key regulator of their diverse roles in nuclear organization, chromatin stability, DNA repair, and cell cycle progression. However, the functions of many of these PTMs remain uncharacterized. Here, we demonstrat...
ORGANISM(S): Homo sapiens (Human) 
2021-01-08 | PXD022974 | Pride

While bacterial metabolism is known to impact antibiotic efficacy and virulence, the metabolic capacities of individual microbes in cystic fibrosis lung infections are difficult to disentangle from sputum samples. Here, we show that untargeted metabolomic profiling of supernatants of multiple str...

2021-05-26 | MTBLS2105 | MetaboLights
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