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ProteomicsTMT-based proteomics of BMDMs following virus infection
To identify potential regulators involved in virus-triggered innate immune response, we used tandem mass tagging (TMT)-based shotgun proteomic analysis of murine bone marrow-derived macrophages (BMDMs) following sendai virus (SeV) infection. This approach facilitated the identification and relative ...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-03 | PXD051098 | Pride
Mus bmdms 
ProteomicsImmunoprecipitation and Mass Spectrometry Reveals Interactors of CD11b
We aimed to identify CD11b-associated inhibitory receptors,that control phagocytosis when engaged by ligands expressed on cancer cells. CD11b was immunoprecipitated from mouse bone marrow-derived macrophages (BMDMs), and the associated proteins were analyzed using mass spectrometry. A few inhibitory...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-17 | PXD063540 | Pride
Mac-1 Cd200r1 Cd11b Bmdms 
ProteomicsMouse BMDMs and Erythrophagocytosis LCMSMS
Reticuloendothelial macrophages engulf ~0.2 trillion senescent erythrocytes daily in a process called erythrophagocytosis (EP). This critical mechanism preserves systemic heme-iron homeostasis by regulating red blood cell (RBC) catabolism and iron recycling. Although extensive work has demonstrated ...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-27 | PXD017788 | Pride
Mouse Rbcs Bmdms Lcmsms 
TranscriptomicsExpression data from mouse bone marrow-derived macrophages (BMDMs)
To recruit phagocytes, apoptotic cells characteristically release ATP, which functions as a “danger” signal. Here, we found that the culture supernatant of apoptotic cells activated the macrophages to express anti-inflammatory genes such as NR4A and Thbs1. A high level of AMP accumulated in the apop...
ORGANISM(S): Mus musculus 
2014-06-24 | E-GEOD-50883 | biostudies-arrayexpress
GenomicsNGS5439 - BMDMs cytokine response
NGS5439 - BMDMs cytokine response
PRJNA1116551 | ENA
TranscriptomicsMG53 TG and MG53 KO mice BMDMs compared to their littermates WT
Using MG53-TG and MG53-KO mice derived BMDMs to operate RNAseq.
ORGANISM(S): Mus musculus 
2025-11-16 | E-MTAB-15824 | biostudies-arrayexpress
TranscriptomicsGenome wide Affymetric Microarray analysis for RIPK1 dependent inflammatory changes in Bone Marrow Derived Macrophages (BMDMs)
Gene level expression estimate using the Whole Transcript (WT) Assay approach of the Gene 1.0 ST Array System for Mouse. This assay was done to identify the RIPK1-dependent gene expression changes in mouse BMDMs. Cost-effective gene-level analysis based on whole-transcript coverage. We analyzed Bone...
ORGANISM(S): Mus musculus 
2016-09-07 | E-GEOD-72797 | biostudies-arrayexpress
TranscriptomicsRole of JunD in macrophage activation under LPS stimulation
To investigate the effects of the differences seen in the JUND binding patterns between LEW, WKY and WKY.LCrgn2 bone marrow derived macrophages (BMDMs), we have 1) analysed gene expression changes over a time course (4 time points: 0,2,4 and 8 hrs) of stimulation with lipopolysaccharide (LPS) using ...
ORGANISM(S): Rattus norvegicus 
2013-04-01 | E-MEXP-3469 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of vehicle- vs LPS-treated primary BMDMs from WT or interleukin-1alpha nuclear localisation sequence mutant mice
We generated a mouse with a mutated IL-1alpha nuclear localisation sequence, causing loss of pro-IL-1alpha nuclear localisation. We tested whether this loss of nuclear pro-IL-1alpha affected the transcriptional response of primary BMDMs to LPS priming. Primary BMDMs from WT or mNLS mice were treate...
ORGANISM(S): Mus musculus 
2026-02-28 | E-MTAB-16641 | biostudies-arrayexpress
GenomicsMus musculus strain:C57BL/6J
Mus musculus BMDMs Raw sequence reads
PRJNA1444843 | ENA
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