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ProteomicsC-terminal amides mark proteins for degradation via SCF/FBXO31
FBXO31 is a substrate adapter for the SCF-type ubiquitin ligase complex SCF/FBXO31 which ubiquitylates C-terminal amide-bearing proteins (CTAPs), thereby triggering their proteasomal degradation in human cells. Profiling of active cullin-RING ubiquitin E3 ligases was performed in naive or FBXO31 kno...
ORGANISM(S): Homo sapiens (Human) 
2024-11-07 | PXD055518 | Pride
Ligase Cullin Fbxo31 Ring Scf Ubiquitin E3 
UnknownA large-scale multi-ancestry genome-wide association study of chronic prostatitis/chronic pelvic pain syndrome in men.
Not available
S-EPMC12789528 | biostudies-literature
UnknownSingle-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.
Not available
S-EPMC11406458 | biostudies-literature
UnknownCandidate SNP associations of optimism and resilience in older adults: exploratory study of 935 community-dwelling adults.
Not available
S-EPMC4163500 | biostudies-literature
UnknownA multi-ancestry meta genome-wide association study of migraine among veterans: associations with traumatic brain injury, depression, and post-traumatic stress disorder.
Not available
S-EPMC12863721 | biostudies-literature
UnknownGenes and environment: novel, functional polymorphism in the human cathepsin L (CTSL1) promoter disrupts a xenobiotic response element (XRE) to alter transcription and blood pressure.
Not available
S-EPMC3478326 | biostudies-literature
UnknownGenetic architecture distinguishes tinnitus from hearing loss.
Not available
S-EPMC10799010 | biostudies-literature
TranscriptomicsHyper-excitability of Neurons generated from Patients with Bipolar Disorder
Bipolar Disorder (BD) is a complex neuropsychiatric disorder that is characterized by intermittent episodes of mania and depression and, without treatment, 15% of patients commit suicide1. Hence, among all diseases, BD has been ranked by the WHO as a top disorder of morbidity and lost productivity2....
ORGANISM(S): Homo sapiens 
2015-10-30 | E-GEOD-58933 | biostudies-arrayexpress
UnknownGene-environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach.
Not available
S-EPMC8055541 | biostudies-literature
UnknownDifferential responses to lithium in hyperexcitable neurons from patients with bipolar disorder.
Not available
S-EPMC4742055 | biostudies-literature
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