Sort   by:  
 Page size 
ProteomicsMass spectrometry analysis of proteins interacting with STAT3
Mass spectrometry analysis of proteins interacting with STAT3¬Flag was performed. STAT3-Flag was transiently expressed in HeLa cells and the interactome of STAT3-Flag was studied in lysosomal extracts. proteins co-¬immunoprecipitating with STAT3--Flag identified eight subunits of the vacuolar H+-¬ A...
ORGANISM(S): Homo sapiens (Human) 
2018-08-29 | PXD006788 | Pride
Co-immunoprecipitation Stat3 
ProteomicsLysosomal alterations in senescence
Lysosomes were isolated from proliferating and oncogene induced senescent cells and subject to LS-MS and proteomic analysis
ORGANISM(S): Homo sapiens (Human) 
2023-02-03 | PXD034358 | Pride
Lysosome Cultivated cells 
ProteomicsMouse female hippocampus proteomics of Alzheimer Tg-SwDI Model
Cerebral Amyloid Angiopathy (CAA) is a significant comorbidity in almost all cases of Alzheimer’s disease (AD) and is unaddressed by current treatment regimens. We explored the Tg-SwDI mouse model which expresses human Amyloid Precursor Protein with the familial Swedish AD mutation as well as the va...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD055083 | Pride
Alzheimer's Mouse Brain Proteomics 
ProteomicsDiabetic Polyneuropathy Patients Exhibit an Altered Skeletal Muscle Proteome
Diabetic polyneuropathy (DPN) is a nerve debilitating condition associated with diabetes that can affect motor nerves and thus potentially affect skeletal muscle health. 15 participants, divided into three groups, were mapped by TMT based proteomics. The participants were classified from clinical di...
ORGANISM(S): Homo sapiens (Human) 
2026-10-22 | PXD061639 | Pride
Human Proteomics Tmt Polyneuropathy Muscle Diabetes Lc-ms/ms 
ProteomicsQuantitative Proteomics Reveals Metabolic Reprogramming during ETHE1 Deficiency, Part 1
Deficiency of mitochondrial sulfur dioxygenase (ETHE1) causes the severe metabolic disorder ethylmalonic encephalopathy, which is characterized by early-onset encephalopathy and defective cytochrome C oxidase because of hydrogen sulfide accumulation. Although the severe systemic consequences of the ...
ORGANISM(S): Mus musculus (Mouse) 
2016-04-11 | PXD002741 | Pride
Metabolism Persulfide dioxygenase Acetylation Sulfide Liver Mouse Ethe1 Itraq Lc-ms/ms 
ProteomicsQuantitative Proteomics Reveals Metabolic Reprogramming during ETHE1 Deficiency, Part 2
Deficiency of mitochondrial sulfur dioxygenase (ETHE1) causes the severe metabolic disorder ethylmalonic encephalopathy, which is characterized by early-onset encephalopathy and defective cytochrome C oxidase because of hydrogen sulfide accumulation. Although the severe systemic consequences of the ...
ORGANISM(S): Mus musculus (Mouse) 
2016-04-11 | PXD002742 | Pride
Metabolism Persulfide dioxygenase Acetylation Sulfide Liver Mouse Ethe1 Itraq Lc-ms/ms 
ProteomicsLC-MS/MS proteomics of ETHE1 deficient patient fibroblasts_Study-1
The mitochondrial enzyme ETHE1 is a persulfide dioxygenase essential for cellular sulfide detoxification, and its deficiency causes the severe and complex inherited metabolic disorder ethylmalonic encephalopathy (EE). In spite of well-described clinical symptoms of the disease, detailed cellular and...
ORGANISM(S): Homo sapiens (Human) 
2018-11-07 | PXD009880 | Pride
Patient fibroblasts Ethe1 deficiency Tmt labeling Lc-ms/ms ethylmalonic acid encephalopathy 
ProteomicsLarge scale proteomics of cholesteatoma
The study describes comprehensive proteomics data of the cholesteatoma disease. Cholesteatoma is a serious and destructive growth of keratinizing squamous epithelium in the middle ear, with a poorly understood etiopathogenesis. The large scale proteomics approach used in this study highly expands ou...
ORGANISM(S): Homo sapiens (Human) 
2014-06-04 | PXD000457 | Pride
Biopsy Tympanic membrane Mucosa Middle ear Patient Cholesteatoma Epithel 
ProteomicsLiver proteomics of rats fed a high fat diet
S-soluble phase
ORGANISM(S): Rattus norvegicus (Rat) 
2010-12-03 | PRD000818 | Pride
ProteomicsSynaptosome Proteomics, Fraction 3
Synaptosomes were isolated by Percoll gradient centrigation and iTRAQ based nanoLC-MS/MS proteomics. Three synapse fractions were studied from three kind of experimental rat groups namely, stressed with anhedonia, stress resilient and unstressed controls.
ORGANISM(S): Rattus norvegicus (Rat) 
2016-04-27 | PXD001776 | Pride
Depression Brain Rat Anhedonic Stress Synapses 
Sort   by:  
 Page size