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Glycolysis is upregulated in cells under specific conditions, such as hypoxia and high energy demand, to achieve the metabolic requirements for continued cell proliferation. However, the mechanism of this increased glycolytic rate remains poorly understood. In the budding yeast Saccharomyces cerevis...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2017-07-24 | PXD006686 | Pride
osteocyte is the mechanosensor in bone, taking up pivotal position in mediating the mechano-induced bone remodeling. Dimagnetic levitation has been used to stimulating a reduced gravity environment for studing the effects of changed gravity to different organisms.we constructed a superconducting mag...
ORGANISM(S): Mus musculus 
Atypical myopathy (AM) is a severe rhabdomyolysis syndrome that occurs in grazing horses. Despite the presence of toxins in their blood, all horses from the same pasture are not prone to display clinical signs of AM. The objective of this study was to compare the blood metabolomic profiles of horses...
2021-08-31 | MTBLS2579 | MetaboLights
Many archetypal and emerging classes of small-molecule therapeutics form covalent 38 protein adducts. In vivo, both the resulting conjugates and their off-target side conjugates have the potential to elicit antibodies, with implications for allergy and drug sequestration. Although β-lactam antibioti...
ORGANISM(S): Homo sapiens (Human) Gallus gallus (Chicken) 
2024-08-08 | PXD052026 | Pride
Effects of six compounds on stem cell neural development.
ORGANISM(S): Mus musculus 
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