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ProteomicsMetabolic reprogramming of Vibrio cholerae impaired in respiratory NADH oxidation is accompanied with increased copper sensitivity
The electrogenic, sodium ion translocating NADH:quinone oxidoreductase (NQR) from Vibrio cholerae is frequent in pathogenic bacteria and a potential target for antibiotics. NQR couples the oxidation of NADH to the formation of a sodium motive force (SMF) and therefore drives important processes such...
ORGANISM(S): Vibrio cholerae O395 
2018-06-21 | PXD009379 | Pride
Nqr Comparative proteomics Lc-ms Vibrio cholerae Na+- translocating nadh:quinone oxidoreductase Sodium bioenergetics Copper tolerance 
ProteomicsChinese hamster ovary (CHO) cell Surfaceome LC-MSMS and mRNA expression analysis
The production of biopharmaceuticals relies on robust cell systems that can produce recombinant proteins at high levels, and grow and survive in the stressful bioprocess environment. Chinese hamster ovary cells (CHO) as the main production hosts offer a variety of advantages including robust growth ...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2022-10-15 | PXD033581 | Pride
Lc-msms Signaling pathways Mrna expression Cho cells Surfaceome 
ProteomicsComparative investigations on surfactin as an antimicrobial metabolite
Surfactin is described as one of the most powerful biosurfactants and is natively produced by Ba-cillus subtilis in notable quantities. In addition to other industrially relevant characteristics, anti-microbial properties were highlighted for surfactin. To investigate this property, stress ap-proach...
ORGANISM(S): Escherichia coli Bacillus subtilis subsp. subtilis str. 168 Pseudomonas putida KT2440 Corynebacterium glutamicum ATCC 13032 Bacteria 
2022-05-20 | PXD029668 | Pride
Proteomics Biosurfactants Bacillus subtilis Stress response Surfactin Cell adaptation 
ProteomicsBiocontrol potentials and proteomic response of lipopeptide producing B. velezensis strains to Diaporthe spp.
Lipopeptide biosurfactant producing Bacillus strains have many useful applications in biotechnology and agriculture, based on their emulsifying, surface activity and antimicrobial properties. In the current study, lipopeptide production kinetics, and biocontrol potentials of two new B. velezensis st...
ORGANISM(S): Bacillus velezensis Bacteria 
2023-10-24 | PXD035016 | Pride
Surfactin Bacillus Biocontrol Lipopeptide Antimicrobial Fengycin Agriculture Proteomics Bacillomycin Iturin Lc-ms/ms 
ProteomicsThe cellular response towards lanthanum is substrate specific and reveals a novel route for glycerol metabolism in Pseudomonas putida KT2440
Ever since the discovery of the first rare earth element (REE)-dependent enzyme,the physiological role of lanthanides has become an emerging field of research due to the environmental implications and biotechnological opportunities. In Pseudomonas putida KT2440, the two pyrroloquinoline quinone-depe...
ORGANISM(S): Pseudomonas putida KT2440 
2020-05-14 | PXD013011 | Pride
Pseudomonas putida Pedh Lanthanides Glycerol metabolism Gark Dehydrogenases Rare earth elements Proteome Pede Pqq 
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