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The placenta is a highly dynamic organ that supports the growth and development of the fetus throughout the different stages of pregnancy. Malfunction of the placenta causes disorders of the pregnancy, including preeclampsia and pre-term birth. The study of the pathophysiology of the placenta at dif...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD072837 | Pride
Trophoblast organoids derived from placental villi provide a 3D model system of human placental development, but access to first-trimester tissues is limited. Here we report that trophoblast stem cells isolated from naïve human pluripotent stem cells (hPSCs) can efficiently self-organize into 3D ste...
ORGANISM(S): Homo sapiens 
2022-04-29 | GSE172241 | GEO
A murine model that mimic the decidualization and regression observed in human was used to investigate the molecular mechanisms underlying the dynamic processes in endometrium. Ovariectomized mice were treated sequentially with steroid hormones and then, to induce decidualization, oil was injected i...
ORGANISM(S): Mus musculus 
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