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ProteomicsProteomic Insight into the Role of Exosomes in Proliferative Vitreoretinopathy Development
To characterize vitreous humor (VH) exosomes and to explore their role in the development of proliferative vitreoretinopathy (PVR) using mass-spectrometry based proteome profiling.
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD028539 | Pride
Exosome Proliferative vitreoretinopathy Vitreous humor Lc-ms/ms 
GenomicsscRNAseq of mouse proliferative vitreoretinopathy
scRNAseq of mouse proliferative vitreoretinopathy
PRJNA1146480 | ENA
GenomicsTranscriptional Characterisation of Proliferative Vitreoretinopathy
Transcriptional Characterisation of Proliferative Vitreoretinopathy
PRJNA744251 | ENA
TranscriptomicsGene Expression Profile of Epiretinal Fibrous Membrane Associated with Proliferative Vitreoretinopathy
Proliferative vitreoretinopathy (PVR) is a severe vision-threatening disorder characterized by the formation of cicatricial fibrous membranes leading to traction retinal detachment. As the pathophysiology remains unclear, there has been no effective therapeutic approach to date other than vitreoreti...
ORGANISM(S): Homo sapiens 
2012-09-21 | E-GEOD-41019 | biostudies-arrayexpress
ProteomicsEffect of 3’,4’-dihydroxyflavonol eye drops in a rat model of dispase-induced proliferative vitreoretinopathy
Proliferative vitreoretinopathy (PVR) was induced in a rat model using intravitreal dispase to study fibrosis- and inflammation-related proteome changes and to evaluate the therapeutic effect of topical 3’,4’-dihydroxyflavonol (DiOHF) eye drops. Retina and vitreous were collected 28 days post-injury...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-01-05 | PXD068151 | Pride
Arpe-19 3’ 4’-dihydroxyflavonol Proliferative vitreoretinopathy  proteomics  rat mod-el of dispase-induced pvr. 
GenomicsSingle‑cell RNA sequencing unveils fibroblast heterogeneity in proliferative vitreoretinopathy membranes
Single‑cell RNA sequencing unveils fibroblast heterogeneity in proliferative vitreoretinopathy membranes
PRJNA1249038 | ENA
GenomicsSingle-cell RNA-sequencing reveals the heterogeneity of microglia in fibrous membrane derived from proliferative diabetic retinopathy and proliferative vitreoretinopathy
Single-cell RNA-sequencing reveals the heterogeneity of microglia in fibrous membrane derived from proliferative diabetic retinopathy and proliferative vitreoretinopathy
PRJNA697911 | ENA
TranscriptomicsscRNAseq of mouse proliferative vitreoretinopathy
We performed single cell transcriptional profiling of mouse proliferative vitreoretinopathy (PVR), to decipher the molecular mechanisms underlying mouse PVR fibrogenesis. In this study, through combination of the single-cell transcriptional profiling and genetic tracing, we provided comprehensive di...
ORGANISM(S): Mus musculus 
2025-09-05 | GSE274480 | GEO
GenomicsScreening of differentially expressed genes and microRNAs in rabbits with traumatic proliferative vitreoretinopathy based on high-throughput sequencing
Screening of differentially expressed genes and microRNAs in rabbits with traumatic proliferative vitreoretinopathy based on high-throughput sequencing
PRJNA1207048 | ENA
ProteomicsThe baseline vitreous proteome in rhegmatogenous retinal detachment: a case–control study of proliferative vitreoretinopathy
Quantitative proteomic analysis of undiluted human vitreous biopsies collected at the time of primary surgical repair of rhegmatogenous retinal detachment (RRD), comparing patients who later developed proliferative vitreoretinopathy (PVR; n=8) with matched RRD controls who did not (n=8). Vitreous sa...
ORGANISM(S): Homo sapiens (Human) 
2026-05-05 | PXD077831 | Pride
Pvr Tmt-10-plex Proteomics Vitreous Ocular Retinal detachment Biomarker Proliferative vitreoretinopathy 
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