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MetabolomicsMetabolome and proteome changes in skeletal muscle and blood of pre-weaning calves fed leucine and threonine supplemented diets

In pre-weaning calves, both leucine and threonine play important roles in growth and muscle metabolism. In this study, metabolomics, proteomics and clinical chemistry were used to assess the effects of leucine and threonine supplementation added to milk replacer on 14 newborn Holstein male calves...

2020-02-20 | MTBLS1045 | MetaboLights
ProteomicsSpatial proteomics of skeletal muscle using thin cryosections reveals metabolic adaption at the muscle-tendon transition zone
Morphological studies of skeletal muscle tissue have provided detailed insights into the architecture of muscle fibers, the surrounding cells, and the extracellular matrix. However, a spatial proteomics analysis of the skeletal muscle, including the muscle-tendon transition zone, is lacking. Here, w...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-22 | PXD046596 | Pride
Mtj Skeletal muscle Spatial proteomics 
ProteomicsZAKb is a cellular compression sensor that mediates hypertrophic signaling in skeletal muscle
Mechanosensing is required for the senses of touch and hearing, and impacts on cellular processes such as cell differentiation, migration, invasion and tissue homeostasis. Mechanical inputs give rise to p38- and JNK-signaling, which mediates adaptive physiological responses in various tissues. In mu...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-31 | PXD028548 | Pride
Zak Phosphoproteomics Mouse. muscle 
TranscriptomicsTranscription profiling of mouse soleus muscle from hormone sensitive lipase-null animals
Expression analysis in order to elucidatethe role of hormone-sensitive lipase in soleus muscle.
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-1772 | biostudies-arrayexpress
ProteomicsExercise beneficially reshapes fasted rat skeletal muscle involving the combined action of beta-hydroxybutyrate and palmitoleic acid
We previously observed that mild exercise causes structural and functional modifications in fasted skeletal muscle, both in rodents and humans. Wistar rats, housed at thermoneutrality, were submitted to mild exercise during a 66h-period of fasting by five 30-min-treadmill runs at 15 m/min without in...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2026-02-18 | PXD074027 | Pride
Fasting Exercise Beta-hydroxybutyrate Lipidome Palmitoleic acid Proteome Muscle 
ProteomicsThe ambiguous Caveolin-3 G55S sequence variant: Muscle biopsy findings and cell biological analysis
Caveolins are structural and functional proteins in plasma membrane invaginations called caveolae. Mutations in Caveolin-3 cause myopathies of variable severity. The pathogenicity of the Caveolin-3 variant G55S is still unclear. Here, we report on three patients suffering from mild to moderate myopa...
ORGANISM(S): Homo sapiens (Human) 
2018-07-05 | PXD003719 | Pride
Lgmd1d Rcmh Caveolin-3 Proteome profile of muscle cells 
ProteomicsIn vitro Protein Expression Profile of Cultivated Muscle Cells from Labeo rohita
A quantitative proteomics approach was used to investigate in Labeo rohita cell line across three passages P1, P15 and P25. A new cell line developed from the muscle tissue of L. rohita (LR) was utilized to understand the proteome in-depth. Comparative proteome analysis was performed for LR muscle ...
ORGANISM(S): Labeo rohita (Indian major carp) 
2025-02-19 | PXD059501 | Pride
Cell culture Labeo rohita Myogenesis Lc-ms/ms 
UnknownIn vitro protein expression profile of cultivated muscle cells from Labeo rohita.
Not available
S-EPMC11836462 | biostudies-literature
ProteomicsSmooth muscle cell spheroids as 3D model of phenotypic plasticity and matrix deposition revealed by 2D-3D proteomics
Our study aims to compare 2D adherent and 3D floating (spheroid) cell cultures of in the context of cellular physiology and in atherosclerosis modelling. Here, we utilize vascular smooth muscle cells from rat aorta to profile 2D and 3D proteomes.
ORGANISM(S): Rattus norvegicus (Rat) 
2026-09-07 | PXD069144 | Pride
Smoot muscle cell  spheroids  3d cell culture  lc-ms/ms 
ProteomicsMesenchymal Stromal Cells: What are the secrets of their secretome?
Multipotent Mesenchymal Stromal Cells (MSCs) are multipotent adult cells that can be isolated from different tissues. The current hypothesis supports that the main MSCs action mechanism relates to its paracrine activity, creating a microenvironment with trophic signals. However, preclinical studies ...
ORGANISM(S): Homo sapiens (Human) 
2016-12-09 | PXD003978 | Pride
Mesenchymal stromal cells Proteome Secretome 
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