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System-wide quantification of the cell surface proteotype and identification of extracellular glycosylation sites is challenging when sample is limiting. We miniaturized and automated the previously described Cell Surface Capture technology increasing sensitivity, reproducibility, and throughput. We...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2019-12-11 | PXD013627 | Pride
Different cell isolation techniques exist for transcriptomic and proteotype profiling of brain cells. Here we show that standard enzymatic digestion of brain tissue at 37°C induces profound alterations in the transcriptome and proteotype of specific brain cells, as compared to cold mechanical dissoc...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD015592 | Pride
Enzymatic dissociation induces transcriptional and proteotype bias in brain cell populations
Different cell isolation techniques exist for transcriptomic and proteotype profiling of brain cells. Here, we provide a systematic investigation of the influence of different cell isolation protocols on transcriptional and proteotype profiles in mouse brain tissue by taking into account single-cell...
ORGANISM(S): Mus musculus 
2020-10-26 | GSE143796 | GEO
Listeria monocytogenes is an opportunistic foodborne pathogen responsible for listeriosis, the third most common foodborne disease. Many different Listeria strains and seroptypes exist, however a proteogenomic resource which would provide a basis for bridging the gap in the molecular understanding b...
ORGANISM(S): Listeria Monocytogenes Egd-e (ncbitaxon:169963) Listeria Monocytogenes Str. Scott A (ncbitaxon:1027396) 
2019-06-01 | MSV000083881 | MassIVE
Listeria monocytogenes is an opportunistic foodborne pathogen responsible for listeriosis, a potentially fatal foodborne disease. Many different Listeria strains and serotypes exist, buthowever a proteogenomic resource that which would allow to bridges the gap in ourthe molecular understanding of th...
ORGANISM(S): Listeria Monocytogenes 
2021-01-26 | PXD014294 | panorama
A central goal of modern biology is to understand the molecular basis of phenotype evolution between species. Previously, the evolutionary profiling at the molecular level has been largely limited to the nucleotide level. Nevertheless, the genotype is translated to proteotype through comprehensive a...
ORGANISM(S): Bos taurus (Bovine) Sus scrofa (Pig) Homo sapiens (Human) Oryctolagus cuniculus (Rabbit) Canis lupus Monodelphis domestica Felis catus (Cat) (Felis silvestris catus) Rattus norvegicus (Rat) Ovis aries Macaca mulatta (Rhesus macaque) Equus caballus (Horse) 
2022-09-22 | PXD028979 | Pride
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