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ProteomicsTargeted analysis of PTPN14, YAP1, LATS1 and GFP SH-tagged pulldown
Targeted analysis of YAP1, LATS1 and PTPN14 interactome
ORGANISM(S): Homo sapiens (Human) 
2023-03-04 | PXD032221 | Pride
Yap1 Lats1 Ptpn14 Apms 
ProteomicsThe tyrosine phosphatase Pez (PTPN14) inhibits metastasis by altering protein trafficking
PTPN14 coordinately regulates receptor trafficking and secretion to modulate metastasis.
ORGANISM(S): Homo sapiens (Human) 
2016-06-08 | PXD001739 | Pride
Breast cancer Tyrosine phosphatase Mass spectrometry Pez Ptpn14 Metastasis 
ProteomicsAP-MS_XL experiment to characterize YAP1/LATS/PTPN14 complex
In this project we investigated the topological composition of ternary complex PTPN14/LATS1/PTPN14. For this purpose, we performed affinity purification with Strep tag of Strep-HA YAP1 and subsequent XL reaction.
ORGANISM(S): Homo sapiens (Human) 
2023-03-04 | PXD039440 | Pride
Xl  yap1  ap-ms 
GenomicsGene expression profile of PTPN14 silence with PDGF-BB stimulation in HA-VSMCs
Gene expression profile of PTPN14 silence with PDGF-BB stimulation in HA-VSMCs
PRJNA1109836 | ENA
GenomicsFenofibrate-mediated inhibition of tumor proliferation and progression by modulating the PTPN14/MARK/Hippo signaling axis
Fenofibrate-mediated inhibition of tumor proliferation and progression by modulating the PTPN14/MARK/Hippo signaling axis
PRJNA1287771 | ENA
UnknownPTPN14 promotes gastric cancer progression by PI3KA/AKT/mTOR pathway.
Not available
S-EPMC10006225 | biostudies-literature
UnknownPTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.
Not available
S-EPMC6226225 | biostudies-literature
UnknownStathmin levels alter PTPN14 expression and impact neuroblastoma cell migration.
Not available
S-EPMC7000740 | biostudies-literature
UnknownPTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes.
Not available
S-EPMC7039277 | biostudies-literature
TranscriptomicsFenofibrate-mediated inhibition of tumor proliferation and progression by modulating the PTPN14/MARK/Hippo signaling axis
PTPN14 is a non-receptor tyrosine phosphatase that functions as a tumor suppressor through negative regulation of the Hippo signaling pathway, making it a potential therapeutic target for cancer. Despite its therapeutic potential, no PTPN14-targeting small-molecules have been developed to date. In t...
ORGANISM(S): Mus musculus 
2026-07-10 | GSE301941 | GEO
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