Sort   by:  
 Page size 
ProteomicsAP-MS_XL experiment to characterize YAP1/LATS/PTPN14 complex
In this project we investigated the topological composition of ternary complex PTPN14/LATS1/PTPN14. For this purpose, we performed affinity purification with Strep tag of Strep-HA YAP1 and subsequent XL reaction.
ORGANISM(S): Homo sapiens (Human) 
2023-03-04 | PXD039440 | Pride
Xl  yap1  ap-ms 
ProteomicsAP-BNPAGE YAP1 complexes separation
YAP1 complexes separation with affinity purification (AP) coupled to BNPAGE
ORGANISM(S): Homo sapiens (Human) 
2023-03-04 | PXD030061 | Pride
Yap1 ap-bnpage 
ProteomicsMS Analysis In vivo treatment of YAP1 SH tagged with phosphatase inhibitors
Investigation of YAP1 interactome plasticity via APMS
ORGANISM(S): Homo sapiens (Human) 
2023-03-04 | PXD032218 | Pride
Phospho Yap1 Apms 
TranscriptomicsRole of Yes-Associated Protein 1 (YAP1) in rhabdomyosarcoma
Doxycycline-inducible YAP1 S127A-driven rhabdomyosarcoma (RMS) tumors, control skeletal muscle and regressed tumors following YAP1 normalization by doxycycline withdrawal were compared to determine the YAP1-regulated gene expression profile relevant to RMS formation. To characterize the role of YAP1...
ORGANISM(S): Mus musculus 
2014-08-12 | E-GEOD-47198 | biostudies-arrayexpress
TranscriptomicsOver-expression of YAP1 in NCI-H716 colorectal cancer cells
YAP1 plays importance roles in development of colorectal cancer as evidenced by their overexpression in colorectal cancer and their expression promoted cell proliferation and survival of colorectal cancer cells. In order to understand potential roles of YAP1 in colorectal cancer, we over-expressed c...
ORGANISM(S): Homo sapiens 
2015-02-04 | E-GEOD-50490 | biostudies-arrayexpress
Transcriptomicshuman hTERT-RPE1 cell spheroid : Control siRNA transfected vs. YAP1 siRNA transfected
Transcriptional profiling of human hTERT-RPE1 cell spheroids comparing Control siRNA transfected hTERT-RPE1 cell spheroids with those transfected with YAP1 siRNA. Two-condition experiment, Control siRNA vs.YAP1 siRNA hTERT-RPE1 cell spheroids. Biological replicates: 1 Control siRNA, 1YAP1 siRNA tran...
ORGANISM(S): Homo sapiens 
2015-02-01 | E-GEOD-54146 | biostudies-arrayexpress
ProteomicsTargeted analysis of PTPN14, YAP1, LATS1 and GFP SH-tagged pulldown
Targeted analysis of YAP1, LATS1 and PTPN14 interactome
ORGANISM(S): Homo sapiens (Human) 
2023-03-04 | PXD032221 | Pride
Yap1 Lats1 Ptpn14 Apms 
GenomicsYAP1 exerts its transcriptional control via TEAD mediated activation of enhancers
YAP is the principle effector of the Hippo signaling pathway; a key regulator of tissue homeostasis whose dysregulation is linked to cancer development. YAP regulation of gene expression is thought to involve the TEAD transcription factor family. Here we show that YAP and TEAD1 binding always co-occ...
ORGANISM(S): Homo sapiens 
2015-08-25 | E-GEOD-61852 | biostudies-arrayexpress
TranscriptomicsKRAS and YAP1 converge to regulate EMT and tumor survival
Cancer cells that express oncogenic alleles of RAS typically require sustained expression of the mutant allele for survival, but the molecular basis of this oncogene dependency remains incompletely understood. To identify genes that can functionally substitute for oncogenic RAS, we systematically ex...
ORGANISM(S): Mus musculus 
2014-07-27 | E-GEOD-56175 | biostudies-arrayexpress
GenomicsThe Hippo tranducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation
The Hippo pathway effector YAP1 controls stem cell fate in epithelial tissues, but its role in stem cells of non-epithelial tissues, such as skeletal muscle, is poorly documented. Here we show that sustained YAP1 activity in mouse activated satellite cells in vivo induces rhabdomyosarcoma (RMS) rese...
ORGANISM(S): Homo sapiens 
2014-08-12 | E-GEOD-55186 | biostudies-arrayexpress
Sort   by:  
 Page size