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ProteomicsA multi-year longitudinal harmonization of quality controls in mass spectrometry proteomics core facilities.
As part of the Core for Life Proteomics Working group, we have undertaken a four-year harmonization study to enhance the comparability of quality control results, identifying community reference values, intra-laboratory performance drifts, sources of heterogeneity, and improvement opportunities. The...
ORGANISM(S): Homo sapiens (Human) 
2024-10-11 | PXD049444 | Pride
Human Proteomics Quality control Core for life Harmonization Qcloud 
ProteomicsA SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Purposing
An outbreak of the novel coronavirus SARS-CoV-2, the causative agent of COVID-19 respiratory disease, has infected over 170,000 people since the end of 2019, killed over 7,400, and caused worldwide social and economic disruption. SARS-CoV-2 infection has a mortality rate of 3.4% among confirmed case...
ORGANISM(S): Homo sapiens (Human) 
2020-03-23 | PXD018117 | Pride
Sars-cov-2 Ppi Coronavirus Covid-19 
ProteomicsBioenergetic fitness and transcriptional–proteomic competence of ARI0002h CAR-T cell infusion products determine response in relapsed multiple myeloma
BCMA-directed CAR-T cell therapy achieves high initial response rates in relapsed or refractory multiple myeloma. However, sustained disease control is mantained in only a subset of patients and its intrinsic determinants are poorly defined. We performed integrated pre-infusion bioenergetic, transcr...
ORGANISM(S): Homo sapiens (Human) 
2026-09-30 | PXD081759 | Pride
Car-t Bcma Transcriptomics Foxo1 Myeloma Proteomics Bioenergetics 
ProteomicsCOFRADIC N-Terminomics approach for the identification of new type II metacaspases potential targets
Our aim is the identification of new potential targets of metacaspases via the use of a metacaspase sextuple mutant for type II metacaspases.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-07-08 | PXD049287 | Pride
Arabidopsis N-terminomics Cofradic Roots 
ProteomicsPneumococcus suppresses host inflammatory response through COMMD2 mediated NF-κB degradation by aggrephagy
NF-κB driven cellular immunity is essential for both pro- and anti-inflammatory responses to microbes, which makes it one of the most frequently targeted pathways by bacteria during pathogenesis. How NF-κB tunes the epithelial response to Streptococcus pneumoniae across the spectrum of commensal to ...
ORGANISM(S): Streptococcus pneumoniae TIGR4 
2026-09-07 | PXD043886 | Pride
Commd2 Nf-κb degradation 
Proteomicscross linking mass spectrometry of Exo84 pulldown in Sec9 and Sec18 depletion mutants
Co-Immunoprecipitation with Crosslinking Using DSS for Exo84 Subunit Sample Preparation: Yeast strains expressing Exo84-3xGFP and FRB-tagged Sec18 or Sec9 were cultured in YPD at 30°C until OD600 0.8-1. Cells were harvested, washed with resuspension buffer (50 mM HEPES, 150 mM NaCl, protease inhibi...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2026-01-21 | PXD061766 | Pride
Crosslinking Saccharomyces cerevisiae Lc-ms/ms 
Proteomics"Plasma proteome profiling of resistant and susceptible chickens during highly pathogenic avian influenza infection
This study investigated the host response to highly pathogenic avian influenza (HPAI) infection in chickens. Birds were classified as resistant (no clinical signs, mortality, histopathological lesions, or positive immunohistochemistry results) or susceptible (showing disease progression). Plasma sam...
ORGANISM(S): Gallus gallus (Chicken) 
2026-09-14 | PXD067000 | Pride
Lc-msms Plasma Chicken Proteomic 
ProteomicsCollecting and analysing pig mucosal scraping samples for mass spectrometry-based proteomics: a study on factors causing variation in proteomic data
In this study, we evaluated the effects of experimenter handling, batch effects, and animal-specific variation on proteomic analyses of mucosal scrapings in pigs. We analysed mucosal samples from twelve piglets that were fed two distinct diets. Mucosal samples were obtained from a 60 cm segment col...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-06-13 | PXD059931 | Pride
Pig  intestine  mucosa  lc-msms  protein extraction dia 
ProteomicsDetection of Complex I and II in BN-PAGE gels
Study of the fully assembled complex I and complex II in mitochondria of oocytes.
ORGANISM(S): Mus musculus (Mouse) Xenopus laevis (African clawed frog) 
2022-05-09 | PXD025371 | Pride
Bn-page Complex ii Complex i Etc 
ProteomicsCharacterization of a lipid-based jumbo phage compartment as a hub for early phage infection
Viral genomes are most vulnerable to cellular defenses at the start of the infection. A family of jumbo phages related to phage ΦKZ, which infects Pseudomonas aeruginosa, assembles a protein-based phage nucleus to protect replicating phage DNA, but how it is protected prior to phage nucleus assembly...
ORGANISM(S): Pseudomonas aeruginosa PAO1-VE2 Pseudomonas phage phiKZ 
2024-11-26 | PXD049415 | Pride
Apms Pseudomonas aeruginosa Phage 
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