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ProteomicsUnbiased quantitative analysis of the cardiac phosphoproteome in response to acute β-adrenergic receptor stimulation in vivo
We utilised Super-SILAC mouse technology to perform an unbiased, quantitative analysis of the cardiac phosphoproteome in mice acutely treated in vivo with either saline or isoprenaline (ISO), a non-selective β-AR agonist. Using a customized mass spectrometry-based workflow (Figure 1), our study iden...
ORGANISM(S): Mus musculus (Mouse) 
2021-12-30 | PXD025569 | Pride
Phosphoproteome  mass spectrometry  β-adrenergic receptor  silac 
ProteomicsArabidopsis diurnal LFQ proteome and labelled phosphoproteome
Plant growth and survival depends to a large extent on the diurnal regulation of cellular processes. Although extensively studied at the transcript level, notably less is known about diurnal fluctuations at the protein level. Here, we report a high-resolution quantitative time-course of the Arabidop...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2020-12-18 | PXD007600 | Pride
Diurnal Phosphoproteome Arabidopsis Proteome 
ProteomicsMurine hippocampal phosphoproteome LC-MSMS
The hippocampus plays an important role in spatial memory and the conversion of short-term to long-term memory. Several studies have reported the presence of a peripheral oscillator in the hippocampus, and have highlighted the importance of circadian regulation in memory formation. In this study we ...
ORGANISM(S): Mus musculus (Mouse) 
2017-04-11 | PXD005669 | Pride
Circadian Hippocampus Phosphoproteome Mouse 
ProteomicsComprehensive evaluation of RNAlater effect on proteome and phosphoproteome
Tumors such as pancreatic cancer contain a variety of enzymes including DNases, RNases and proteases which may lead to autolysis of DNA, RNA and proteins during sample processing. In general, RNAlater can be used to keep nucleic acids intact since it contains high concentrations of quaternary ammoni...
ORGANISM(S): Homo sapiens (Human) 
2019-05-06 | PXD010710 | Pride
Rnalater Proteome Phosphoproteome 
UnknownIntegrated quantitative analysis of the phosphoproteome and transcriptome in tamoxifen-resistant breast cancer.
Not available
S-EPMC3013041 | biostudies-literature
ProteomicsPhosphoproteome profiling using the isobaric carrier without the need for phosphoenrichment
Phosphorylation is a crucial component of signaling cascades in a cell. It controls various biological cellular functions such as cell growth and apoptosis. Due to the low stoichiometry of phosphorylaion, enrichment of phosphopeptide prior to LC-MS/MS is necessary for comprehensive phosphoproteome a...
ORGANISM(S): Homo sapiens (Human) 
2022-03-07 | PXD028490 | Pride
Isobaric labeling Tmt Carrier Phosphoproteome Quantitative proteomics 
ProteomicsComparative proteomics and phosphoproteomics analyses of glucocorticoid responses in breast cancer cell lines
Breast cancer is often treated with glucocorticoids together with chemotherapy to relieve its side effects. However, it has been reported that glucocorticoids promote metastasis of breast cancer. In this study, we conducted quantitative mass-spectrometry to acquire proteome and phosphoproteome to un...
ORGANISM(S): Homo sapiens (Human) 
2026-01-26 | PXD070780 | Pride
Phosphoproteome Glucocorticoid Breast cancer Proteome 
UnknownQuantitative phosphoproteome on the silkworm (Bombyx mori) cells infected with baculovirus.
Not available
S-EPMC5477107 | biostudies-literature
ProteomicsRice-xoo interaction phosphoproteome LC-MSMS
A comprehensive quantitative phosphoproteome analysis of rice in response to bacterial blight at 0h and 24h after xoo infection
ORGANISM(S): Oryza sativa (Rice) 
2015-06-29 | PXD002222 | Pride
Lc-msms Phosphoproteome Xoo Rice 
ModelsYugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 1
Yugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 1 Insulin induces phosphorylation and activation of liver-type phosphofructokinase 1, which thereby controls a key reaction in glycolysis. This mechanism is revealed using the mathematical model. In this model, the PFKL ph...
2024-09-02 | BIOMD0000000540 | BioModels
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