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ProteomicsRelaxin-2: shaping the proteomic landscape of skeletal muscle physiology, glucose trafficking, and mitochondrial function in rat.
Relaxin-2 is a hormone with robust beneficial effects on the heart and blood vessels and with a potential therapeutic efficacy in cardiovascular (CV) disease. Considering the interorgan communication between skeletal muscle and heart, and the relation between muscle quality/composition and CV events...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-09-21 | PXD078619 | Pride
Serelaxin Phosphoproteome Mitochondrial respiration Metabolism. Skeletal muscle Relaxin-2 Myogenesis Proteome 
GenomicsExpression profiling in OVCAR8 cells following treatment with relaxin-2 (RLN2)
Expression profiling in OVCAR8 cells following treatment with relaxin-2 (RLN2)
PRJNA635380 | ENA
TranscriptomicsExpression profiling in OVCAR8 cells following treatment with relaxin-2 (RLN2)
The relaxin-RXFP1 signaling loop promotes survival and proliferation in a panel of high-grade serous ovarian (HGSOC) cancer cell lines. Knockdown of either the relaxin receptor-1(RXFP1) or relaxin-2 (RLN2) decreased growth and tumorigenicity and increased apoptosis in dependent HGSOC cell lines. Tra...
ORGANISM(S): Homo sapiens 
2020-12-31 | GSE151280 | GEO
ProteomicsIdentification and Quantification of Human Relaxin Proteins by Immunoaffinity-Mass Spectrometry
We developed immunoaffinity-selected reaction monitoring assays for the measurment of human relaxin-1 and relaxin-2 proteins in biological and clinical samples.
ORGANISM(S): Homo sapiens (Human) 
2024-07-04 | PXD051230 | Pride
Relaxin h2 Relaxin h1 Rel1_human Mass spectrometry Rln2 Prostate Rln1 Immunoaffinity Rel2_human Maternal serum Enzyme-linked immunosorbent assay 
UnknownIntraarticular injection of relaxin-2 alleviates shoulder arthrofibrosis.
Not available
S-EPMC6589647 | biostudies-literature
UnknownRelaxin-2 as a Potential Biomarker in Cardiovascular Diseases.
Not available
S-EPMC9317583 | biostudies-literature
UnknownDistinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxin.
Not available
S-EPMC5468325 | biostudies-literature
UnknownA novel role for relaxin-2 in the pathogenesis of primary varicosis.
Not available
S-EPMC3380868 | biostudies-literature
UnknownFurther Developments towards a Minimal Potent Derivative of Human Relaxin-2.
Not available
S-EPMC10454739 | biostudies-literature
UnknownRelaxin-2 plasma levels in atrial fibrillation are linked to inflammation and oxidative stress markers.
Not available
S-EPMC9789945 | biostudies-literature
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