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MetabolomicsPilot Study 13C flux effects when RhoC or RhoA perturbed (13C BCs)
Not available
ORGANISM(S): Homo sapiens 
ST000282 | MetabolomicsWorkbench
ProteomicsRhoA ko BMDC - Control of Homeostasis and Dendritic Cell Survival by the GTPase RhoA
Differential protein expression between RhoA ko and wt bone marrow-derived dendritic cells
ORGANISM(S): Mus musculus (Mouse) 
2015-10-01 | PXD001636 | Pride
Rhoa Dendritic cells 
ProteomicsBistability in the Rac1, PAK and RhoA signalling network is a feature of cell motility.
Dynamic interactions between RhoA and Rac1, members of the Rho small GTPase family, play a vital role in the control of cell migration. Using predictive mathematical modelling and experimental validation in MDA-MB-231 mesenchymal breast cancer cells, we show that Rac1 and RhoA interactions via the P...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080751 | MassIVE
TranscriptomicsTranscription profiling of human normal and RhoA immortal cells
Rho family small GTPases serve as molecular switches in the regulation of diverse cellular functions including actin cytoskeleton remodeling, cell migration, gene transcription, and cell proliferation. Importantly, Rho overexpression is frequently seen in many carcinomas. However, published studies...
ORGANISM(S): Homo sapiens 
2008-10-26 | E-GEOD-12917 | biostudies-arrayexpress
ProteomicsMembers of the RhoA subfamily of Rho GTPases interfere with HPV E6-mediated stimulation of the ubiquitin ligase E6AP
The E3 ubiquitin ligase E6AP, encoded by the UBE3A gene, plays a prominent role in cancers induced by human papillomaviruses (HPVs). In complex with the HPV E6 oncoprotein, it targets for instance the tumor suppressor p53 for degradation, thereby contributing to HPV-induced cellular transformation. ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD069463 | Pride
E6ap Rhoa Hpv E6 Ube3a Ubiquitination Mass spectrometry In-gel 
TranscriptomicsConstitutively active RhoA (RhoAV14) expression and regulation of acqeous humor outflow dynamics
Impaired drainage of aqueous humor through the trabecular meshwork (TM) culminating in increased intraocular pressure is a major risk factor for glaucoma, a leading cause of blindness worldwide. Regulation of aqueous humor drainage through the TM, however, is poorly understood. The role of RhoA GTPa...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-9288 | biostudies-arrayexpress
ProteomicsMembers of the RhoA subfamily of Rho GTPases interfere with HPV E6-mediated stimulation of the ubiquitin ligase E6AP
The E3 ubiquitin ligase E6AP, encoded by the UBE3A gene, plays a prominent role in cancers induced by human papillomaviruses (HPVs). In complex with the HPV E6 oncoprotein, it targets for instance the tumor suppressor p53 for degradation, thereby contributing to HPV-induced cellular transformation. ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD069396 | Pride
E6ap Rhoa Hpv E6 Ube3a Ubiquitination Xl-ms 
TranscriptomicsRHOA inactivation enhances Wnt signaling and promotes colorectal cancer
Microarray transcriptomic analysis of formalin-fixed, paraffin-embedded small intestinal tumors from control (Apcmin/+;Vil-Cre-/-;RhoADN/-) and DN-RhoA (Apcmin/+;Vil-CreTG/-;RhoADN/-) mice.
ORGANISM(S): Mus musculus 
2014-11-21 | E-MTAB-2981 | biostudies-arrayexpress
ProteomicsIdentification of novel RHOA interacting patners
RHO subfamily of small GTPases comprise highly conserved family members RHOA, RHOB, and RHOC which cycle between GTP-bound 'active' and GDP-bound 'inactive' states. In the active form, RHO proteins interact with a variety of downstream effector proteins, controlling their activity and function. Many...
ORGANISM(S): Homo sapiens (Human) 
2016-11-01 | PXD004934 | Pride
Silac  lc-ms  protein-protein interactions  rhoa 
ProteomicsMembers of the RhoA subfamily of Rho GTPases interfere with HPV E6-mediated stimulation of the ubiquitin ligase E6AP
The E3 ubiquitin ligase E6AP, encoded by the UBE3A gene, plays a prominent role in cancers induced by human papillomaviruses (HPVs). In complex with the HPV E6 oncoprotein, it targets for instance the tumor suppressor p53 for degradation, thereby contributing to HPV-induced cellular transformation. ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD069419 | Pride
E6ap Rhoa Hpv E6 Ube3a Lip-ms Ubiquitination 
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