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Proteomicsβ-actin RNA-BioID
Function and fate of mRNAs is controlled by RNA binding proteins (RBPs) but determining the proteome of a specific mRNA in vivo is still challenging. RNA proximity biotinylation on the transported β-actin mRNA tagged with MS2 aptamers (RNA-BioID) is used to characterize the dynamic proteome of the β...
ORGANISM(S): Mus musculus (Mouse) 
2020-03-12 | PXD010694 | Pride
Mouse Rna localization Rbps Bioid 
ProteomicsRNA-BioID of lncRNA HOTAIR in Flp-In T-REx cells
Accumulating evidence highlights the role of long non-coding RNAs (lncRNA) in cellular homeostasis, and their dysregulation in disease settings. Most lncRNAs function by interacting with proteins or protein complexes. While several orthogonal methods have been developed to identify these proteins, e...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD029058 | Pride
Lncrna Hotair Rna-bioid 
ProteomicsThe comprehensive interactomes of human adenosine RNA methylases and demethylases revealed by proximity labelling-mass spectrometry.
N6-methyladenosine (m6A) and N6,2′-O‐dimethyladenosine (m6Am) are two abundant modifications found in mRNAs and ncRNAs that can regulate multiple aspects of RNA biology and function mainly through regulation of interaction with specific RNA-binding proteins. Both modifications are linked to developm...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD021566 | Pride
Bioid M6am Rna methyltransferase Rna modification M6a Rna demethylase 
ProteomicsIdentification of BRCA2-DSS1 new partner HELZ
R-loops are dynamic three-stranded nucleic acid structures that regulate genome function but can threaten genome stability if not properly resolved. BRCA2, a key player in homologous recombination (HR), also regulates R-loops, though the mechanisms remain unclear. To uncover novel R-loop regulators,...
ORGANISM(S): Homo sapiens (Human) 
2025-12-30 | PXD066766 | Pride
Hela Biotinid-dss1 Brca2 Helz 
ProteomicsYoun_et_al_RNAbodies_SAINT3105_Set1
This set of submissions contains the mass spectrometry files for the manuscript by Ji-Young Youn et al. that describes the high-density proximity mapping of RNA bodies. BioID experiments were performed from Flp-In T-REx HEK293 cells and MS files were acquired on Orbitrap Elite and Orbitrap Velos.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-08-04 | MSV000081411 | MassIVE
ProteomicsYoun_et_al_RNAbodies_SAINT3105_Set2
This set of submissions contains the mass spectrometry files for the manuscript by Ji-Young Youn et al. that describes the high-density proximity mapping of RNA bodies. BioID experiments were performed from Flp-In T-REx HEK293 cells and MS files were acquired on Orbitrap Elite and Orbitrap Velos. T...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-08-04 | MSV000081412 | MassIVE
Unknownβ-Actin mRNA interactome mapping by proximity biotinylation.
Not available
S-EPMC6600913 | biostudies-literature
ProteomicsCLUH interactome reveals its association to SPAG5 and its proximity to the translation of mitochondrial proteins
Mitochondria require thousands of proteins to fulfil their essential function in energy production and other fundamental biological processes. These proteins are mostly encoded by the nuclear genome, translated in the cytoplasm before being imported into the organelle. RNA binding proteins (RBPs) ar...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-12-13 | PXD027158 | Pride
Cluh Turboid Rna binding protein Mitochondrial proteins Bioid 
ProteomicsYoun_et_al_RNAbodies_SAINT3105_Set3
This set of submissions contains the mass spectrometry files for the manuscript by Ji-Young Youn et al. that describes the high-density proximity mapping of RNA bodies. BioID experiments were performed from Flp-In T-REx HEK293 cells and MS files were acquired on Orbitrap Elite and Orbitrap Velos. D...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-08-04 | MSV000081413 | MassIVE
UnknownCharacterization of RBP9 and RBP10, two developmentally regulated RNA-binding proteins in Trypanosoma brucei.
Not available
S-EPMC5413900 | biostudies-literature
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