Sort   by:  
 Page size 
ProteomicsIdentification of proteins bound with RPA194 at rDNA loci in hypoxic breast cancer cells
We combined chromatin immunoprecipitation (ChIP) with mass spectrometry to identify key bidning partners of RPA194 (the major subunit of RNA polI) at the rDNA loci in breast cancer cells subjected to hypoxia.
ORGANISM(S): Homo sapiens (Human) 
2025-07-15 | PXD053040 | Pride
Rpa194 Breast cancer Hypoxia Chip-ms 
ProteomicsIdentification of proteins bound with RPA194 at rDNA loci post radiation in breast cancer cells
Following radiation damage, cells resume ribosome biogenesis for survival. We combined chromatin immunoprecipitation (ChIP) with mass spectrometry to identify key binding partners of RPA194 (the major subunit of RNA polI) at the rDNA loci in response to irradiation.
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD041472 | Pride
Breast cancer Rdna Rpa194 Radiation Chip-ms Ir 
ProteomicsIdentification of proteins bound with RPA194 at rRNA loci in primary versus metastatic breast cancer cells
The nucleolus, the site of ribosome biogenesis, serves as a central hub for sensing and responding to cellular stress and plays a crucial role in this process; furthermore, emerging evidence highlights the potential role of ribosome biogenesis in driving metastasis. A combined approach of chromatin ...
ORGANISM(S): Homo sapiens (Human) 
2025-07-27 | PXD060651 | Pride
Breast cancer Rpa194 Chip Metastasis 
GenomicsDeconvolution ChIP-seq profiling of UBF and RPA194 in K562 cells to identify analogous enhancer structures on mouse and human ribosomal RNA genes
The combination of Chromatin Immunoprecipitation and Massively Parallel Sequencing, or ChIP-Seq, has greatly advanced our genome-wide understanding of chromatin and enhancer structures. However, its resolution at any given genetic locus is limited by several factors. In applying ChIP-Seq to study th...
ORGANISM(S): Homo sapiens 
2017-12-31 | E-MTAB-6032 | biostudies-arrayexpress
GenomicsGenome-wide analysis of the RNA polyemerase I trascription factor UBF1/2 binding in mouse and human cell lines.
We report ChIP-Seq analysis of the RNA polyemerase I trascription factor UBF1/2 in NIH3T3, HMEC and HMLER cell lines. NIH3T3* samples: We correlated UBF1/2 binding across the genome with that of RNA polemerase I (Pol I), RNA polemerase II (Pol II) and chromatin states in NIH3T3 cells We perfromed Ch...
ORGANISM(S): Mus musculus 
2014-11-14 | E-GEOD-63255 | biostudies-arrayexpress
UnknownProtective Effect Against Cancer of Antibodies to the Large Subunits of Both RNA Polymerases I and III in Scleroderma.
Not available
S-EPMC6717013 | biostudies-literature
UnknownIdentification of an E3 ligase that targets the catalytic subunit of RNA Polymerase I upon transcription stress.
Not available
S-EPMC9727647 | biostudies-literature
UnknownNucleolar structure connects with global nuclear organization.
Not available
S-EPMC10846622 | biostudies-literature
UnknownRelocalization of upstream binding factor to viral replication compartments is UL24 independent and follows the onset of herpes simplex virus 1 DNA synthesis.
Not available
S-EPMC2863781 | biostudies-literature
UnknownDCAF13-mediated K63-linked ubiquitination of RNA polymerase I promotes uncontrolled proliferation in Breast Cancer.
Not available
S-EPMC11718263 | biostudies-literature
Sort   by:  
 Page size