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ProteomicsUltrasonic-based OCT-removal from solid tumor biopsies.
A new method for proteomic studies of OCT-embedded samples based on ultrasound energy is proposed. The cleaning of OCT from mouse kidney embedded tissues were evaluated through the aid of ultrasound energy, with two different frequencies. Simultaneously, vortex agitation was used as control. The opt...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2019-06-13 | PXD013164 | Pride
Oct-embedded samples Ultrasound energy Renal oncocytoma Mass spectrometry. Chromophobe renal cell carcinoma Sample treatment 
ProteomicsUltrasonic-based filter aided sample preparation as the general method to sample preparation in proteomics
In this work, we propose a new high-throughput ultrafast method for large scale proteomics approaches by speeding the classic filter aided sample preparation protocol, FASP. The new US-FASP method matches the analytical minimalism roles as time, cost, sample requirement, reagent consumption, energy ...
ORGANISM(S): Mus musculus (Mouse) Escherichia coli 
2020-06-08 | PXD018360 | Pride
Mus musculus Label-free quantification E. coli Ultrasonic-assisted sample preparation Fasp Lc-ms/ms 
ProteomicsPathway-guided monitoring of the disease course in bladder cancer with longitudinal urine proteomics
In this work, we introduce a new concept we have developed and tested, named the differential Personal Pathway index (dPPi). This tool extracts and summates comprehensive disease-specific information contained within an individual’s proteome as a holistic way to follow the response to disease and me...
ORGANISM(S): Homo sapiens (Human) 
2023-01-16 | PXD025139 | Pride
Urine Lc-msms Bladder cancer Precision medicine Label-free quantification 
ProteomicsChromophobe renal cell carcinoma versus renal oncocytoma: a proteomic approach
The proteome of clinical tissue samples diagnosed with chromophobe renal cell carcinomas (chRCC) and renal oncocytomas (RO) were evaluated to establish a potential discriminative biomarker panel of proteins for these two tumors subtypes.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD022018 | Pride
Mass spectrometry Renal cancer Chromophobe renal cell carcinoma Proteins Biomarkers renal oncocytoma 
ProteomicsRenal cell carcinoma: a proteomic approach
The proteome of clinical tissue samples diagnosed with clear cell renal cell carcinoma (ccRCC) and papillary renal cell carcinoma (pRCC) were evaluated analyzed along with the dataset identifier PXD022018 to establish a potential discriminative biomarker panel of proteins for these tumors subtypes.
ORGANISM(S): Homo sapiens (Human) 
2021-12-15 | PXD023296 | Pride
Clear cell renal cell carcinoma Renal oncocytoma Mass spectrometry Label-free quantification. Renal tumors Chromophobe renal cell carcinoma Papillary renal cell carcinoma Proteins Biomarkers 
ProteomicsSnap-heated freeze-free preservation and processing of the urine proteome
New method for urine proteome preservation and processing based on thermal stabilization and FASP digestion. Four urine proteomes were preserved during 48 h and 6 months using (i) the classic freeze preservation at -20 °C, (ii) snap-heated freeze-free preservation at laboratory temperature (20 °C) a...
ORGANISM(S): Homo sapiens (Human) 
2020-01-10 | PXD012880 | Pride
Stabilizor-based technology Lc-msms Human urine Fasp Proteome preservation 
UnknownGlobal burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.
Not available
S-EPMC7567026 | biostudies-literature
UnknownFive insights from the Global Burden of Disease Study 2019.
Not available
S-EPMC7116361 | biostudies-literature
UnknownElective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.
Not available
S-EPMC7272903 | biostudies-literature
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