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MetabolomicsThe Sphingolipidome of the model organism Caenorhabditis elegans
Sphingolipids are important lipids and integral members of membranes, where they form small microdomains called lipid rafts. These rafts are enriched in cholesterol and sphingolipids, which influences biophysical properties. Interestingly, the membranes of the biomedical model organism Caenorhabditi...
2024-04-01 | MTBLS963 | MetaboLights
ProteomicsA High-salt diet induces immune-independent re-differentiation of melanoma, metabolic shut down and cell-cycle arrest
A high salt diet (HSD) is known to reduce cancer growth in some models, due to accumulation of sodium in the skin, which enhanced local anti-tumor immunity. Here we show that a HSD inhibits melanoma growth in both skin and lung, independent from sodium accumulation and from immune cells. Melanoma ce...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-02 | PXD057160 | Pride
Melanogenesis Tmtpro Mouse Lc-ms3 Melanoma High salt diet 
MetabolomicsChemodiverse cell systems responses to UV in an algal sister of land plants

Plant terrestrialization necessitated overcoming a barrage of stressors. Embryophytes (land plants) use an integrated response network to adjust their molecular physiology in response to terrestrial stressors—one of the important stressors is UV irradiance. The zygnematophytes are the closest str...

2026-07-01 | MTBLS8088 | MetaboLights
UnknownPeritoneal Dialysis Fluid Supplementation with Alanyl-Glutamine Attenuates Conventional Dialysis Fluid-Mediated Endothelial Cell Injury by Restoring Perturbed Cytoprotective Responses.
Not available
S-EPMC7765520 | biostudies-literature
UnknownMeprin β Modulates Brevican Proteolysis Impairing Neural Plasticity and Memory Formation.
Not available
S-EPMC12093287 | biostudies-literature
TranscriptomicsImmunosuppressive capabilities of mesenchymal stromal cells are maintained under hypoxic growth conditions and after gamma irradiation
To investigate factors that might influence the T-cell suppressive capabilities of mesenchymal stroma cells, T-cell suppressive and non-suppressive mesenchymal stroma cells were compared. Immunosuppressive capabilities of MSCs was determined via T-cell proliferation assay.
ORGANISM(S): Homo sapiens 
2015-01-20 | E-MTAB-2396 | biostudies-arrayexpress
UnknownHippo Signaling Regulates High-NaCl-Induced Increase in RORγt+ Pro-Inflammatory Lymphocytes.
Not available
S-EPMC11900413 | biostudies-literature
UnknownMicrocephaly is associated with impaired educational development in children with congenital heart disease.
Not available
S-EPMC9584804 | biostudies-literature
TranscriptomicsTranscription profiling of human childhood B-lineage ALL patients reveals five distinct biological processes and 14 differentially expressed genes characterize TEL/AML1-positive leukemia
Background; The t(12;21)(p13;q22) translocation is found in 20 to 25% of cases of childhood B-lineage acute lymphoblastic leukemia (B-ALL). This rearrangement results in the fusion of ETV6 (TEL) and RUNX1 (AML1) genes and defines a relatively uniform category, although only some patients suffer very...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9170 | biostudies-arrayexpress
UnknownUnderstanding Cell Model Characteristics-RNA Expression Profiling in Primary and Immortalized Human Mesothelial Cells, and in Human Vein and Microvascular Endothelial Cells.
Not available
S-EPMC9563025 | biostudies-literature
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