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ProteomicsLIver Glycogen SWATH Proteomics
Identification and relative quantification of proteins associated with mammalian liver glycogen.
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) Rattus norvegicus (Rat) 
2018-07-23 | PXD009140 | Pride
Glycogen Human Liver Mouse Glycogenin Rat 
ProteomicsS-Trap eliminates Pluronic F68 and cell culture media polymers for effective proteomic analysis of mammalian cell bioreactor supernatants
Proteomic analysis of bioreactor supernatants can inform on cellular metabolic status, viability, and productivity, as well as product quality, which can in turn help optimize bioreactor operation. Incubating mammalian cells in bioreactors requires the addition of polymeric surfactants such as Pluro...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2020-06-30 | PXD017214 | Pride
Polymer contaminants Alkylation Bottom-up proteomics Mass spectrometry Sp3 Sample preparation S-trap Bioreactor samples 
UnknownRapid improvement in spinal pain in patients with axial spondyloarthritis treated with secukinumab: primary results from a randomized controlled phase-IIIb trial.
Not available
S-EPMC8544765 | biostudies-literature
ProteomicsStructure and antigenicity of divergent Henipavirus fusion glycoproteins
A novel henipavirus (HNV) named Langya virus (LayV) was isolated in human patients in China in August 2022. It is closely related to Mòjiāng virus (MojV) and represents the first instance of HNV zoonosis to humans outside of Nipah virus (NiV) and Hendra viruses (HeV). Within this work, mass spectrom...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2023-05-03 | PXD039898 | Pride
Glycoprotein Henipavirus Virus structures 
MetabolomicsGlycerophospholipid remodeling is critical for orthoflavivirus infection

Flavivirus infection is tightly connected to host lipid metabolism. Here, we performed shotgun lipidomics of cells infected with neurotropic Zika, West Nile and tick-borne encephalitis viruses, as well as dengue and yellow fever virus. Early in infection specific lipids accumulated, e.g., neutral...

2025-02-24 | MTBLS11030 | MetaboLights
UnknownCardiovascular magnetic resonance-derived left atrioventricular coupling index and major adverse cardiac events in patients following acute myocardial infarction.
Not available
S-EPMC10099819 | biostudies-literature
ProteomicsCardiovascular symptoms of PASC are associated with trace-level circulatory cytokines that affect the function of primary human cardiomyocytes
Globally, over 65 million individuals are estimated to suffer from post-acute sequelae of COVID-19 (PASC). A large number of individuals living with PASC experience cardiovascular symptoms (i.e. chest pain and heart palpitations) (PASC-CVS). The role of chronic inflammation in these symptoms, in par...
ORGANISM(S): Homo sapiens (Human) 
2024-11-01 | PXD050202 | Pride
Human Long covid Plasma Pasc 
ProteomicsElectron-Activated Dissociation and Collision-Induced Dissociation Glycopeptide Fragmentation for Improved Glycoproteomics
Protein glycosylation is a critical PTM for the stability and biological function of many proteins, but full characterisation of site-specific glycosylation of proteins remains analytically challenging. Collision induced dissociation (CID) is the most common fragmentation method used in LC-MS/MS wor...
ORGANISM(S): Homo sapiens (Human) 
2024-07-04 | PXD050173 | Pride
Cid Glycopeptide Ead Zenotof 7600 
UnknownLeft-atrial long-axis shortening allows effective quantification of atrial function and optimized risk prediction following acute myocardial infarction.
Not available
S-EPMC9574426 | biostudies-literature
UnknownRBM20, a gene for hereditary cardiomyopathy, regulates titin splicing.
Not available
S-EPMC3569865 | biostudies-literature
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