Sort   by:  
 Page size 
ProteomicsProteomic analysis of neutrophil extracellular traps (healthy control, rheumatoid arthritis, systemic lupus erythematosus)_C4PR_LIV
Neutrophil Extracellular Traps (NETs) are chromatin-derived extracellular structures that are expelled from neutrophils in response to infectious or inflammatory stimuli. NET DNA structures are decorated with proteins including histones, myeloperoxidase and neutrophil elastase. NETs are implicated i...
ORGANISM(S): Homo sapiens (Human) 
2019-02-18 | PXD011796 | Pride
A23187 Neutrophil extracellular traps Pma Rheumatoid arthritis Systemic lupus erythematosus 
ProteomicsEquine tendon LC-MSMS, C4PR_LIV
the aim of this study was to isolate, characterise and compare the proteome of the IFM and fascicular matrix (FM) in the equine superficial digital flexor tendon (SDFT). We hypothesised that the proteomic profile would differ between the FM and the IFM, with greater complexity and faster turnover in...
ORGANISM(S): Equus caballus (Horse) 
2016-02-08 | PXD002979 | Pride
Lc-msms Fm Equine Tendon Ifm 
ProteomicsProteomic profile of mouse hippocampus following kainate-induced epileptogenesis C4PR_LIV
Anti-epileptogenic agents that prevent the development of epilepsy following a brain insult remain the holy grail of epilepsy therapeutics. In order to identify such drugs, it is necessary to first understand the cellular and molecular events that underlie the epileptogenic process, from initial ins...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-23 | PXD010986 | Pride
Lc-msms Kainic acid Mouse Hippocampus Epileptogenesis 
ProteomicsHeparin-binding proteome in normal pancreas and murine experimental pancreatitis_C4PR_LIV
Acute pancreatitis (AP) is acute inflammation of the pancreas, mainly caused by gallstones and alcohol, driven by changes in communication between cells. Heparin-binding proteins (HBPs) play a central role in cell communication. Therefore, we used heparin affinity proteomics to identify extracellula...
ORGANISM(S): Mus musculus (Mouse) 
2018-12-17 | PXD012039 | Pride
Murine Pancreatitis Heparin-binding proteins (hbps) 
ProteomicsStructure-function Relationships in Human Tendons: Interfascicular Matrix Specialisation in the Achilles Tendon C4PR_LIV
Tendon is a highly aligned connective tissue, in which the macro-structure consists of collagen-rich fascicles surrounded by interfascicular matrix (IFM). In a series of recent studies in equine tissue, we have demonstrated specialisation of tendon composition, structure and mechanics to achieve the...
ORGANISM(S): Homo sapiens (Human) 
2020-11-11 | PXD018212 | Pride
Structure-function Fascicles  interfascicularmatrix  mechanical testing  mass spectrometry  ageing 
ProteomicsAmino acid and heavy water labelling to obtain protein turnover rates in intact adult animals
Both labelling studies were conducted with C57/BL6J adult male mice, derived from the same supplier and maintained under identical conditions. Eleven adult male C57BL/6JOlaHsd mice (Harlan UK Ltd., Shardlow, UK) of over 12 months of age at the start of the experiment were housed individually in 48 x...
ORGANISM(S): Mus Musculus (mouse) 
2021-12-13 | PXD029639 | JPOST Repository
GenomicsWTCCC3_Pre-Eclampsia
WTCCC3 UK maternal cases of pre-eclampsia
EGAD00010000854 | EGA
GenomicsInterPregGen-GWAS-UZB-2
GWAS genotype data for maternal and fetal (baby) cases of preeclampsia and controls from Uzbekistan. This dataset is a component of the InterPregGen FP7 project. DNA samples for this component were collected by InterPregGen Consortium members in Tashkent, Uzbekistan at the Institute of Immunology, U...
EGAD00010001917 | EGA
GenomicsInterPregGen-GWAS-KAZ-3
Preeclampsia (PE) is a syndrome affecting pregnant mothers and fetus/babies characterised by hypertension and proteinuria, and is a leading cause of maternal and fetal death and of premature births worldwide. The InterPregGen Consortium was funded by a European Framework 7 (FP7) grant and grew out o...
EGAD00010001949 | EGA
GenomicsPE-META-CENTRAL_ASIA-MATERNAL
Fixed effect meta-analysis summary statistics combining GWAS of maternal preeclampsia cases and controls from Central Asia (Kazakhstan and Uzbekistan).
EGAD00010001985 | EGA
Sort   by:  
 Page size