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Mass Spectrometry (70)
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UNIPROT ID/AC

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CHEBI ID

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Metabolite Name

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First Public Date

2014 (34)
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Modelling Approach

Ordinary differential equation model (1)

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Lab affiliation

ETH Zurich, Institute of Molecular Systems Biology, Zurich, Switzerland (7)
1 The Rosalind Franklin Institute, Oxfordshire, United Kingdom 2 Department of Pharmacology, University of Oxford (1)
1. Department of Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany, 2. Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JR, United Kingdom; (1)
1. Department of Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany, 2. Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JR, United Kingdom; ( lab head ) (1)
1. School of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia 2. Institute for Glyco-core Research (iGCORE), Nagoya University, Nagoya, Japan (1)
Bioanalytical Mass Spectrometry group, Max-Planck-Institute for Biophysical Chemistry, Goettingen, Germany (1)
Biomolecular Mass Spectrometry and Proteomics, Utrecht University (1)
Cell Biology of Infection Laboratory, The Francis Crick Institute, London, UK Division of Medicine, University College London, London, UK (1)
Cell and Chemical Biology Leiden University Medical Center The Netherlands (1)
Center for Biomedical Mass Spectrometry, Department of Biochemistry, Boston University School of Medicine, Boston, MA, USA (1)
Center for Molecular Medicine, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands (1)
Cheeloo College of Medicine, Shandong University, Jinan 250002, PR.China. Department of Hepatobiliary Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China. Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery, Hefei 230001, China. Anhui Provincial Clinical Research Center for Hepatobiliary Diseases, Hefei 230001, China. (1)
Cheeloo College of Medicine, Shandong University, Jinan 250002, PR.China. Department of Hepatobiliary Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China. Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery, Hefei 230001, China. Anhui Provincial Clinical Research Center for Hepatobiliary Diseases, Hefei 230001, China. (1)
Chemistry Department, Boston College, USA (1)
Departamento de interacción epidemiológica, Instituto Nacional de Salud Pública. Universidad No. 655, Col. Santa María Ahuacatitlán, Cuernavaca, Morelos. CP 62100. México. (1)
Departement of Biology University of Fribourg (1)
Department of Biological Engineering Massachusetts Institute of Technology Cambridge MA 02139, Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology Cambridge MA 02142 USA, Center for Precision Cancer Medicine Massachusetts Institute of Technnology Cambridge MA 02142 USA (1)
Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, Guangdong, China (1)
Department of Genome Sciences, University of Washington (1)
Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Str. 3, Halle/Saale D-01620, Germany Center for Structural Mass Spectrometry, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Str. 3, Halle/Saale D-01620, Germany (1)
Dept. of Biochemistry, Center for Biomedical Mass Spectrometry, Boston University 2Bioinformatics Program, Boston Universty (1)
Dept. of Biological Chemistry, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel (1)
Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, Faculty of Medicine and Health, University of Leeds, UK (1)
EDyP (1)
Harvard Department of Stem Cell and Regenerative Biology Cambridge, MA 02138, USA (1)
IMP, Campus Vienna Biocenter 1, 1030 Vienna, Austria (1)
Institute of Genetics and Cancer (IGC), University of Edinburgh, Edinburgh, Scotland (1)
Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, 8010 Graz, Austria and BioTechMed-Graz, Graz, Austria (1)
Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L69 3BX, United Kingdom (1)
Johns Hopkins University Assistant Professor, Department of Chemistry Assistant Professor, Department of Biology (by courtesy) Assistant Professor, Thomas C. Jenkins Department of Biophysics (by courtesy) Preceptor, Chemistry-Biology Interface (CBI) Program (1)

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bacteria (2)

Modification

15.994915 (2)
42.010565 (2)
-17.026549 (1)
10.008269 (1)
4'-dihydroxyphenylalanine (1)
45.029395 (1)
58.005479 (1)
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Transcription profiling by array (77)
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Site-Link for identification of chromatinized proteome defined by site-specific histone acylations in living cells

By coupling the mass spectrometry, we developed the Site-Link strategy based on the GCE method for analyzing the interacting proteome of histone lysine acylations in living cells. As K* could mimic the natural lysine to be recognized by natural lysine synthase, histones bearing the site-specifically...

ORGANISM(S): Homo sapiens (Human)

2023-03-06 | PXD033959 | Pride

Site-Link for identification of chromatinized proteome defined by site-specific histone acylations in living cells

ORGANISM(S): Homo sapiens (Human)

2023-03-06 | PXD029505 | Pride

Hek293t Histone acylation Site-specific Proteome Lc-ms/ms

Confirmation of direct interaction between H3K56cr and GLYR1 by H3K*56cr Site-Link in living cells

As we have found that H3K56cr can crosslink with GLYR1 in living cells, we now perform H3K*cr Site-Link in GLYR1 overexpressed cells. The subsequent 365-nm light irradiation could activate the diazirine and covalently capture potential effector proteins on native chromatin in living cells. The cross...

ORGANISM(S): Homo sapiens (Human)

2023-03-06 | PXD033960 | Pride

Plink Glyr1 H3k56cr

Interstrand Cross-Link Formation Involving Reaction of a Mispaired Cytosine Residue with an Abasic Site in Duplex DNA.

Not available

S-EPMC8650171 | biostudies-literature

Replication and repair of a reduced 2΄-deoxyguanosine-abasic site interstrand cross-link in human cells.

Not available

S-EPMC5499640 | biostudies-literature

Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.

Not available

S-EPMC3185412 | biostudies-literature

Collagen cross-link profiles and mineral are different between the mandible and femur with site specific response to perturbed collagen.

Not available

S-EPMC9618783 | biostudies-literature

Genome-wide screen reveals rhythmic regulation of genes involved in odor processing in the olfactory epithelium

Odor discrimination behavior displays circadian fluctuations in mice indicating that mammalian olfactory function is under control of the circadian system. This is further supported by the facts that odor discrimination rhythms depend on the presence of clock genes and that olfactory tissues contain...

ORGANISM(S): Mus musculus

2015-11-04 | E-GEOD-69853 | biostudies-arrayexpress

Identification of a histidine-tyrosine cross-link in the active site of the cbb3-type cytochrome c oxidase from Rhodobacter sphaeroides.

Not available

S-EPMC1637549 | biostudies-literature

Model of abasic site DNA cross-link repair; from the architecture of NEIL3 DNA binding domains to the X-structure model.

Not available

S-EPMC9561275 | biostudies-literature

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