Spatially-resolved

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Unknown (2022)
Genomics (550)
Transcriptomics (253)
Proteomics (157)
Other (147)
Metabolomics (13)
Methylation profiling (3)

Organisms

Homo sapiens (248)
Mus musculus (195)
Schizophyllum commune H4-8 (98)
Gallus gallus (10)
synthetic construct (9)
Rattus norvegicus (9)
Danio rerio (6)
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Mesocricetus auratus (3)
Arabidopsis thaliana (3)
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cellular organisms (2)
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Mus (1)
Severe acute respiratory syndrome coronavirus 2 (1)
Mus (1)

Organisms

Homo sapiens (178)
Mus musculus (168)
Gallus gallus (9)
Rattus norvegicus (7)
Danio rerio (5)
Arabidopsis thaliana (5)
Anableps anableps (3)
Mesocricetus auratus (3)
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unidentified (2)
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Escherichia coli str. K-12 substr. MG1655 (1)
Escherichia coli BW25113 (1)
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human skin metagenome (1)
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Caenorhabditis elegans (1)
Escherichia coli (1)
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Repository

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geo (394)
pride (98)
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Disease

Breast cancer (5)
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Cancer (1)
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Inflammation (1)
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Cutaneous malignant melanoma 1 (1)
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Colon mucinous adenocarcinoma (1)
Salivary gland carcinoma (1)
Esophageal carcinoma (1)
Lung adenocarcinoma (1)
Liver disease (1)
Lymphoma (1)
Neuroblastoma (1)
Cardiovascular system disease (1)
Colorectal cancer (1)
Malignant neoplasm of ovary (1)
Wounds and Injuries (1)

Technology Type

Mass Spectrometry (100)
Shotgun proteomics (42)
Bottom-up proteomics (32)
Data-independent acquisition (15)
Data-dependent acquisition (14)
Mass spectrometry imaging (8)
Affinity purification coupled with mass spectrometry proteomics (7)
Top-down proteomics (6)
Mass spectrometry assay (5)
Mass spectrometry (4)
MALDI (2)
Metaproteomics (2)
Affinity proteomics (2)
HDMSE (1)
SRM/MRM (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (17)
Q Exactive Plus (8)
LTQ Orbitrap Velos (7)
N/A (6)
NextSeq 500 (5)
Chromium Next GEM Single Cell Multiome ATAC + Gene Expression Reagent Bundle, (4)
GC MS (4)
10X Genomics reagent kit (3)
Illumina HiSeq 2500 (3)
Illumina HiSeq 4000 (3)
Orbitrap Exploris 480 (3)
GC-MS (3)
Single nuclei were captured using the 10x Genomics Chromium Controller. (2)
10X Chromium Nuclei Isolation Kit (2)
Nanostring GeoMx spatial profiler (2)
LTQ Velos ETD (2)
6520A Quadrupole Time-of-Flight LC/MS (2)
Hamamatsu Nanozoomer S60 (1)
Chromium Next GEM Single Cell Multiome Reagent Bundle (1)
10X Genomics reagents (1)
Mastercycler pro S Thermocyler (Eppendorf); 2100 Bioanalyzer (Agilent) (1)
2100 Bioanalyzer (Agilent); Axio Imager.Z2 (ZEISS) (1)
CryoStar NX70 Cryostat (Epredia) (1)
10X Chromium On-Chip Multiplex (1)
Not applicable (1)
Illumina NovaSeq X (1)
NA (1)
- (1)
DNBSEQ-G400 (1)
Illumina HiSeq 2000 (1)

Publication Date

2026 (155)
2025 (130)
2024 (83)
2023 (71)
2022 (63)
2021 (33)
2016 (16)
2020 (13)
2019 (10)
2017 (5)
2015 (5)
2018 (5)
2014 (2)

CHEBI ID

CHEBI:74374 (1)
CHEBI:74231 (1)
CHEBI:75200 (1)
CHEBI:72065 (1)
CHEBI:74375 (1)
CHEBI:72058 (1)
CHEBI:74465 (1)
CHEBI:74372 (1)
CHEBI:74238 (1)
CHEBI:74371 (1)
CHEBI:74241 (1)
CHEBI:71727 (1)
CHEBI:134236 (1)
CHEBI:71728 (1)
CHEBI:134237 (1)
CHEBI:74369 (1)
CHEBI:74237 (1)
CHEBI:134490 (1)
CHEBI:136239 (1)
CHEBI:141589 (1)
CHEBI:136257 (1)
CHEBI:91039 (1)
CHEBI:136489 (1)
CHEBI:136235 (1)
CHEBI:136225 (1)
CHEBI:173071 (1)
CHEBI:173070 (1)
CHEBI:173069 (1)
CHEBI:173068 (1)
CHEBI:173067 (1)

Metabolite Name

Phosphatidylinositol 38:1(1-) (1)
Phosphatidylinositol 38:2(1-) (1)
Phosphatidylinositol 38:3(1-) (1)
Phosphatidylinositol 38:5(1-) (1)
Phosphatidylinositol 36:1(1-) (1)
Phosphatidylinositol 36:2(1-) (1)
Phosphatidylinositol 34:1(1-) (1)
Phosphatidylinositol 34:2(1-) (1)
Phosphatidylinositol 32:0(1-) (1)
Phosphatidylinositol 32:1(1-) (1)
Phosphatidylserine 36:1(1-) (1)
Phosphatidylserine 36:2 (1)
Phosphatidylglycerol 36:2(1-) (1)
Phosphatidylethanolamine 38:4 zwitterion (1)
Phosphatidylserine 34:1(1-) (1)
Phosphatidylethanolamine 36:1 zwitterion (1)
Phosphatidylethanolamine 36:2 zwitterion (1)
Phosphatidylethanolamine 36:3 (1)
Phosphatidylethanolamine 34:2 zwitterion (1)
Phosphatidic acid 36:2 (1)
Phosphatidic acid 34:1 (1)
Phosphatidylethanolamine 38:2 zwitterion (1)
Phosphatidylinositol 38:4 (1)
Phosphatidylinositol 36:3 (1)
Phosphatidylinositol 36:4 (1)
Phosphatidylglycerol 36:1 (1)
Phosphatidylglycerol 34:1 (1)
LPI(18:0) (1)
Campesta-5,7-dien-3beta-ol (1)
(5Z,7E)-(3S)-25-fluoro-9,10-seco-5,7,10(19)-cholestatrien-3-ol (1)

First Public Date

2026 (158)
2025 (104)
2024 (85)
2023 (58)
2022 (49)
2021 (31)
2020 (10)
2019 (6)
2016 (4)
2017 (3)
2018 (1)
2015 (1)
2014 (1)

Classification

bacteria (3)
protozoa (2)

Study type

Spatial transcriptomics by high-throughput sequencing (10)
Single nucleus RNA sequencing (7)
RNA-seq of coding RNA from single cells (6)
RNA-seq of coding RNA (5)
ScATAC-seq (2)
Single-nucleus ATAC-seq (1)
RNA-seq of non coding RNA from single cells (1)
Human - Single-cell sequencing (1)
Transcription profiling by array (1)
RNA-seq of total RNA (1)

Release Date

2025 (401)
2024 (273)
2023 (271)
2022 (271)
2021 (179)
2020 (118)
2018 (95)
2019 (94)
2017 (80)
2016 (72)
2026 (63)
2015 (42)
2014 (38)
2013 (18)
2012 (10)
2011 (9)
2010 (7)
2008 (7)
2009 (5)
2006 (3)
2007 (1)

Lab affiliation

Division of Molecular and Cellular Function School of Biological Science Faculty of Biology Medicine and Health The University of Manchester Manchester United Kingdom (3)
Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany (2)
hong kong baptist university (2)
Dalian Institute of Chemical Physics (2)
Université de Lille, Sciences et Technologies - INSERM U1192 - Laboratoire PRISM (2)
Director of Women’s Health Research Women’s Service Line Inova Health System (2)
Discovery Proteomics Facility, University of Oxford (2)
Zhengzhou University (2)
University of Hohenheim, Institute of Animal Science, Stuttgart, Germany (2)
Pacific Northwest National Laboratory (2)
Systems Biology Ireland, University College Dublin (2)
Center for Thoracic Cancers, MGH Cancer Center Massachusetts General Hospital Harvard Medical School USA (1)
1. Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark; 2. Proteomics and Singal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany (1)
1Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7FZ, UK (1)
Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9PL, UK. (1)
Univ.Lille, Inserm, CHU Lille, U1192 - Protéomique Réponse Inflammatoire Spectrométrie de Masse - PRISM, F-59000 Lille, France (1)
Professor Department of Biology University of York York United Kingdom (1)
Stress- and Immunoproteomics Group, Molecular and Applied Microbiology Department, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute Jena (1)
1. Center for Translational Biomedical Research, University of North Carolina at Greensboro 2. Department of Chemistry & Biochemistry, University of North Carolina at Greensboro (1)
Sch1School of Pharmacy, Department of Chemistry,University of Wisconsin-Madison, Madison, Wisconsin, 53705, (1)
Discovery Proteomics Lab, University of Oxford (1)
Division of Vascular Oncology and Metastasis Research,German Cancer Research Center (DKFZ), Heidelberg, Germany. European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. (1)
Spatial Proteomics Max Delbrück Center Robert-Rössle-Straße 10 13125 Berlin, Germany (1)
Division of Vascular Oncology and Metastasis Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. (1)
Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Paul-Wittsack Str. 10, 68163, Mannheim, Germany. (1)
Dept. Proteomics and Signal Transduction Max Planck Institute of Biochemistry Am Klopferspitz 18 82152 Martinsried (near Munich) Germany (1)
Nanobio Measurement Group, Division of Biomedical Metrology, Korea Research Institute of Standards and Science, Daejeon 34113, Republic of Korea (1)
Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany. & NNF Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (1)
Institute of chemical technologies and Analytics TU-Wien (1)
Department of Cardiology, Shenzhen Cardiovascular Minimally Invasive Medical Engineering Technology Research and Development Center, Shenzhen People’s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, China (1)

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Spatially resolved integrative analysis of transcriptomic and metabolomic changes in tissue injury studies

Recent developments in spatially resolved -omics have enabled the joint study of gene expression, metabolite levels and tissue morphology, offering greater insights into biological pathways. Integrating these modalities from matched tissue sections to probe spatially-coordinated processes, howeve...

2025-12-03 | MTBLS13445 | MetaboLights

Spatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers

Not available

ORGANISM(S): Mus musculus

ST002219 | MetabolomicsWorkbench

massNet: integrated processing and classification of spatially resolved mass spectrometry data using deep learning for rapid tumor delineation

Not available

ORGANISM(S): Mus musculus

ST002045 | MetabolomicsWorkbench

Spatially resolved proteome profiling of less than 200 cells from tomato fruit pericarp by integrating laser-capture microdissection with nanodroplet sample preparation

Proteomic data from technical developments of a nanoPOTS-based spatially resolved proteome profiling of <200 cells from tomato fruit pericarp.

ORGANISM(S): Solanum lycopersicum

2018-08-21 | PXD010806 | Pride

On-tissue spatially-resolved glycoproteomics guided by N-glycan imaging reveal global dysregulation of canine glioma glycoproteomic landscape

Here we present an approach to identify N-linked glycoproteins and deduce their spatial localization using a combination of MALDI N-glycan MSI and spatially-resolved glycoproteomics. We subjected glioma biopsies to on-tissue PNGaseF digestion and MALDI-MSI and found that the glycan HexNAc4-Hex5-NeuA...

ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris)

2022-05-04 | PXD025537 | Pride

Glioblastoma Spatially resolved glycoproteomics Glycoproteomics Glycan imaging Haptoglobin Sialic acid Spatially resolved glycoproteomicsglycan imaging Maldi-msi Hypersialylation

Spatially Resolved Proteomics via Tissue Expansion

Spatially resolved proteomics is an emerging approach, however, it remains technically challenging due to the complexity of the tissue microsampling techniques and mass spectrometry analysis of nanoscale specimen volumes. Here, we describe an expansion proteomics method ProteomEx, a combination of t...

ORGANISM(S): Mus <genus>

2022-11-04 | PXD037950 |

On-tissue spatially-resolved glycoproteomics guided by N-glycan imaging reveal global dysregulation of canine glioma glycoproteomic landscape

ORGANISM(S): Canis lupus

2023-03-11 | PXD025826 | Pride

Glioblastoma Spatially-resolved Glycoproteomics Haptoglobin Sialic-acid Maldi-msi Hypersialylation Glycan-imaging

Spatially resolved epigenomic profiling of single cells in complex tissues

PRJNA789560 | ENA

Laser capture microdissection-capillary zone electrophoresis-tandem mass spectrometry (LCM-CZE-MS/MS) for spatially resolved top-down proteomics: a pilot study of zebrafish brain

Mass spectrometry (MS)-based spatially resolved top-down proteomics (TDP) of tissues is crucial for understanding the roles played by microenvironmental heterogeneity in the biological functions of organs and for discovering new proteoform biomarkers of diseases. There are few published spatially re...

ORGANISM(S): zebrafish metagenome

2023-03-11 | PXD027741 | Pride

Spatially resolved top-down proteomics capillary zone electrophoresis-tandem mass spectrometry laser capture microdissection zebrafish brain proteoform high sensitivity neuropeptide hormone activity motor activity

Spatially resolved m6A profiling using m6A-ARTR-DBiT

PRJNA1202190 | ENA

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