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ProteomicsOn-tissue spatially-resolved glycoproteomics guided by N-glycan imaging reveal global dysregulation of canine glioma glycoproteomic landscape
Here we present an approach to identify N-linked glycoproteins and deduce their spatial localization using a combination of MALDI N-glycan MSI and spatially-resolved glycoproteomics. We subjected glioma biopsies to on-tissue PNGaseF digestion and MALDI-MSI and found that the glycan HexNAc4-Hex5-NeuA...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2022-05-04 | PXD025537 | Pride
Glioblastoma Spatially resolved glycoproteomics Glycoproteomics Glycan imaging Haptoglobin Sialic acid Spatially resolved glycoproteomicsglycan imaging Maldi-msi Hypersialylation 
ProteomicsOn-tissue spatially-resolved glycoproteomics guided by N-glycan imaging reveal global dysregulation of canine glioma glycoproteomic landscape
Here we present an approach to identify N-linked glycoproteins and deduce their spatial localization using a combination of MALDI N-glycan MSI and spatially-resolved glycoproteomics. We subjected glioma biopsies to on-tissue PNGaseF digestion and MALDI-MSI and found that the glycan HexNAc4-Hex5-NeuA...
ORGANISM(S): Canis lupus 
2023-03-11 | PXD025826 | Pride
Glioblastoma Spatially-resolved Glycoproteomics Haptoglobin Sialic-acid Maldi-msi Hypersialylation Glycan-imaging 
ProteomicsRaw N-glycan MALDI mass spectrometry imaging data on formalin-fixed mouse kidney
The N-glycome was mapped and visualised on formalin-fixed mouse kidney tissue using an ultrafleXtreme MALDI-ToF/ToF MS instrument (Bruker Daltonics).
ORGANISM(S): Mus musculus (Mouse) 
2018-11-02 | PXD009808 | Pride
Formalin-fixed Kidney N-glycan Mouse Maldi Mass spectrometry imaging 
UnknownImaging specific cellular glycan structures using glycosyltransferases via click chemistry.
Not available
S-EPMC5993098 | biostudies-literature
ProteomicsSpatial omics based machine learning (SOML) algorithms for the early detection of hepatocellular carcinoma.
Hepatocellular carcinoma (HCC) is the seventh most common cancer in the world and accounts for over 800,000 deaths annually, making it the second most lethal cancer. Poor chemotherapeutic agents against HCC have necessitated the importance of early detection and surgical intervention in patient mana...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD047546 | Pride
Glycan Spatial-omics Hcc Imaging Maldi_tof 
UnknownBifunctional cleavable probes for in situ multiplexed glycan detection and imaging using mass spectrometry.
Not available
S-EPMC6385553 | biostudies-literature
UnknownN-Linked Glycan Branching and Fucosylation Are Increased Directly in Hcc Tissue As Determined through in Situ Glycan Imaging.
Not available
S-EPMC6784322 | biostudies-literature
UnknownOn-tissue spatially resolved glycoproteomics guided by N-glycan imaging reveal global dysregulation of canine glioma glycoproteomic landscape.
Not available
S-EPMC8617081 | biostudies-literature
UnknownRaw N-glycan mass spectrometry imaging data on formalin-fixed mouse kidney.
Not available
S-EPMC6197570 | biostudies-literature
UnknownNative glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome.
Not available
S-EPMC5620232 | biostudies-literature
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