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ProteomicsAnalysis of proteins proximal to epsin 1 in A549 cells during entry of influenza A virus
Influenza A viruses (IAVs) are respiratory pathogens that represent a global concern due to their ability to cause seasonal epidemics and sporadic pandemics in the human population. Thus, a comprehensive understanding of IAV biology is essential in order to design effective antivirals. It is well es...
ORGANISM(S): Homo sapiens (Human) Influenza A virus (A/WSN/1933(H1N1)) 
2025-05-08 | PXD058908 | Pride
Epsin 1 Proximity labelling Virus entry Turboid Influenza a virus 
ProteomicsPhosphoproteomic-based kinase profiling early in influenza virus infection
Although annual epidemics of seasonal influenza affect around 10% of the global population, current treatment options are limited and development of new antivirals is urgently needed. Here, using state-of-the-art quantitative phosphoproteomics, we reveal the unique phosphoproteome dynamics that occu...
ORGANISM(S): Homo sapiens (Human) Influenza A virus (A/WSN/1933(H1N1)) Gallus gallus (Chicken) 
2018-09-13 | PXD009999 | Pride
Influenza virus Silac Phosphoproteomics 
ProteomicsLimited proteolysis of SARS-CoV-2 Spike treated at pH 2 or pH 7
SARS-CoV-2 is a respiratory virus spreading via aerosol particles. Aerosol particles can exhibit extreme environmental conditions affecting contained viruses, including acidic pH. Here, we study how harsh pH conditions, such as pH 2, can affect the structure of Spike, which is the main protein media...
ORGANISM(S): Homo sapiens (Human) Severe acute respiratory syndrome coronavirus 2 
2025-07-17 | PXD064612 | Pride
Sars-cov-2 Lc-ms Spike Acidic ph Lip 
ProteomicsProtoemics of nasal and bronchial mucus from primary human airway epithelial cells grown at air-liquid interface.
Differentiated primary human respiratory epithelial cells grown at air-liquid interface have become a widely used cell culture model of the human conducting airways. These cultures contain secretory cells such as goblet and club cells, which produce and secrete mucus. Here, we characterize the compo...
ORGANISM(S): Homo sapiens (Human) 
2025-08-13 | PXD066146 | Pride
Lc-msms Human airway epithelial cells Mucus 
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