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ProteomicsNovel Potential Plasma Biomarkers: Exercise-Specific Proteomic Signatures in the Plasma of Racehorses during Training Adaptations and Racing Efforts
Background: Racehorses undergo profound physiological changes in response to training and competition, yet current tools to assess training adaptation and overload remain limited. Traditional biomarkers often fail to reflect the complex molecular dynamics induced by physical effort. This study aime...
ORGANISM(S): Equus caballus (Horse) 
2025-12-20 | PXD067028 | Pride
Exercise Tmtpro Training Horse Plasma Exploris 480 Evosep one 
ProteomicsComparative Analysis of Extracellular Vesicle Isolation from Equine Serum and Plasma
To compare the efficiency, reproducibility, and proteomic profiles of extracellular vesicles (EVs) isolated from equine serum and plasma using size-exclusion chromatography (SEC) and differential ultracentrifugation (UC)+SEC, and to assess how the starting material influences EV cargo. Blood was col...
ORGANISM(S): Equus caballus (Horse) 
2026-01-23 | PXD068077 | Pride
Evs Exploris 480 Horse Sp3 Evosep one Sec uc 
ProteomicsImpaired mitochondrial DNA maintenance in NAFLD: associations between mtDNA copy number, mtDNA damage and BER factors
Non-alcoholic fatty liver disease (NAFLD) is characterized by mitochondrial dysfunction and oxidative stress, potentially compromising mitochondrial DNA (mtDNA) integrity. The contribution of base excision repair (BER) to mtDNA maintenance in NAFLD remains poorly understood. Here, we analyzed mtDNA ...
ORGANISM(S): Homo sapiens (Human) 
2026-08-17 | PXD075974 | Pride
Prm Leukocytes Mitochondria Evosep one Orbitrap astral Surequant 
ProteomicsShotgun analysis of nuclear proteins from mouse brain
Nuclei were isolated from the mouse brain. Proteins were extracted with addition of Bensonase and cleaned up by acetone precipitation. Proteis were resuspended in 50 mM ammonium bicarbonate and PPS Silent Surfactant. Samples were sonicated on ice to improve the solubility of proteins, then alkylated...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000079301 | MassIVE
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