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MetabolomicsTransgenic Tobacco Plants Expressing Synthetic Peptides: A Functional and Structural Analysis for Pathogen Resistance
The emergence of multidrug-resistant pathogens poses a significant threat to human health and agriculture. Current antimicrobial strategies against phytopathogens are often ineffective, failing to ensure food security while contributing to environmental pollution. Synthetic antimicrobial peptides (A...
2025-09-25 | MTBLS12255 | MetaboLights
ProteomicsSystematic characterization of 21 post-translational modification using synthetic peptides
The data presented in this study in the - context of the ProteoemTools project - is based on the synthesis of about 5000 synthetic peptides carrying 21 different post-translational modifications to systematically characterize their chromatographic and mass spectrometric properties using multimodal L...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-04-05 | MSV000091649 | MassIVE
TranscriptomicsSynthetic cationic peptide IDR-1018 modulates human macrophage differentiation
Synthetic, innate defense regulators (IDR) peptides, designed based on natural host defenses peptides, have enhanced immunomodulatory activities and reduced toxicity leading to protection in infection and inflammation models that is dependent on macrophages/monocytes. Here we measured the effect of ...
ORGANISM(S): Homo sapiens 
2013-10-16 | E-GEOD-40131 | biostudies-arrayexpress
ProteomicsA comparative study of synthetic winged peptides for absolute protein quantification
A proper internal standard choice is critical for accurate, precise, and reproducible mass spectrometry-based proteomics assays. Synthetic isotopically labeled (SIL) proteins are currently considered the gold standard. However, they are costly and challenging to obtain. An alternative approach uses ...
ORGANISM(S): Homo Sapiens 
2021-08-17 | PXD027985 | panorama
ProteomicsDigestion of TSN2 and TSN89 synthetic peptides by proteasomes
Proteasomes are large multi-subunit enzymes that act as the main producers of antigenic peptides presented at the cell surface to CD8+ T cells. They can simply cut proteins or ligate non-contiguous peptide fragments thereby generating novel sequences, i.e. spliced peptides via a process called prote...
ORGANISM(S): Homo sapiens (Human) 
2022-12-19 | PXD025995 | Pride
Synthetic peptides Proteasome Digestion Lc-ms/ms 
ProteomicsMass spectral Analysis of Synthetic Peptides: Implications in Proteomics
Tryptic synthetic peptides generated in silico from human proteome are used as standards to evaluate the performance of MS and algorithm used to identify the proteins.
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD017992 | Pride
Peptides Chromatography Human proteome Tandem mass spectrometry Proteomic standards 
ProteomicsDigestion of a variety of synthetic peptides by proteasomes
Proteasomes are large multi-subunit enzymes that act as the main producers of antigenic peptides presented at the cell surface to CD8+ T cells. They can simply cut proteins or recombine their fragments thereby generating novel sequences, i.e. spliced peptides via a process called proteasome-catalyse...
ORGANISM(S): Homo sapiens (Human) 
2020-04-14 | PXD016782 | Pride
Synthetic peptides Proteasome Digestion Lc-ms/ms 
TranscriptomicsMicroarray experiment of Candida albicans treated with synthetic peptides
To investigate the mode of action of a novel class of antifungal synthtic acrylamide peptides, the pathogenic yeast, Candida albicans, was exposed to sublethal doses of peptides with different structures. The experiments include the most effective structure, LH, peptides with no antifungal effects (...
ORGANISM(S): Candida albicans 
2024-06-18 | E-MTAB-13294 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD4+ T cells induced by HIV-1 gp120/V3 loop peptides, time series
Comparative changes of gene expression in human primary CD4+ T cells induced by HIV-1 gp120/V3 loop synthetic peptides, during antigen presentation
ORGANISM(S): Homo sapiens 
2008-09-01 | E-MEXP-1586 | biostudies-arrayexpress
ProteomicsSystematic characterization of 21 post-translational modification using synthetic peptides
The data presented in this study in the - context of the ProteoemTools project - is based on the synthesis of about 5000 synthetic peptides carrying 21 different post-translational modifications to systematically characterize their chromatographic and mass spectrometric properties using multimodal L...
ORGANISM(S): Homo sapiens (Human) 
2018-06-04 | PXD009449 | Pride
Post-translational modification Acetylation Immonium ion Ptm Proteometools Synthetic standard Phosphorylation Diagnostic ion Neutral loss Synthetic peptides 
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