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ProteomicsMass spectrometry of neuroblastoma organoids
Collect proteomic data for organoids from relapsed neuroblastoma patients
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051208 | Pride
Neuroblastoma Dia Organoids 
TranscriptomicsTranscription profiling of human peripheral blood to detect cardiac allograft rejection and response to immunosuppressive therapy
BACKGROUND: Assessment of gene expression in peripheral blood may provide a noninvasive screening test for allograft rejection. We hypothesized that changes in peripheral blood expression profiles would correlate with biopsy-proven rejection and would resolve after treatment of rejection episodes. M...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5967 | biostudies-arrayexpress
ProteomicsGlomerular filtrate proteins in acute cardiorenal syndrome
Acute cardiorenal syndrome (CRS-1) is a morbid complication of acute cardiovascular disease. Mechanistic investigations have focused on intrarenal cellular signaling induced by ischemia/reperfusion. Additional cardiorenal connector signals have been postulated, but investigation in CRS-1 has been li...
ORGANISM(S): Mus musculus (Mouse) 
2019-02-27 | PXD012193 | Pride
Cardiovascular disease Urine Isobaric labeling Mouse model Acute cardiorenal syndrome Quantitative proteomics Tandem mass tags 
ProteomicsSerine-threonine kinase TAO3 mediated trafficking of endosomes containing the invadopodia scaffold TKS5-alpha promotes cancer invasion and tumor growth
Invadopodia are actin-based proteolytic membrane protrusions required for invasive behavior and tumor growth. In this study, we used our high-content screening assay to identify kinases whose activity impacts invadopodia formation. Among the top hits selected for further analysis was TAO3, a STE20-l...
ORGANISM(S): Homo sapiens (Human) 
2021-01-29 | PXD023867 | Pride
Tks5-alpha Taok3 Tao3 Tmt data Invadopodia Endosomes Phosphoproteomics Ptm quantitation Orbitrap fusion 
TranscriptomicsCircadian Transcriptome of the Chicken Pineal In Vitro
Chick pinealocytes exhibit all the characteristics of a complete circadian system, comprising photoreceptive inputs, molecular clockworks and an easily measured rhythmic output, melatonin biosynthesis. We used microarray analysis to investigate the expression of approximately 8000 genes within cult...
ORGANISM(S): Gallus gallus 
2008-07-04 | E-GEOD-5292 | biostudies-arrayexpress
TranscriptomicsTg2576 and wild-type mice treated with PDE9A-inhibitor
Many forms of synaptic plasticity are critically dependent upon production of cGMP to trigger activity-dependent increases in synaptic size and strength. Phosphodiesterase 9A (PDE9A) is a high affinity, cGMP-specific phosphodiesterase with widespread distribution in the central nervous system. Inhib...
ORGANISM(S): Mus musculus 
2012-03-09 | E-GEOD-36237 | biostudies-arrayexpress
TranscriptomicsWhole genome expression analysis in the third-instar larval midgut of Drosophila melanogaster
Survival of insects on a substrate containing toxic substances such as plant secondary metabolites or insecticides is dependent on the metabolism or excretion of those xenobiotics. The primary sites of xenobiotic metabolism are the midgut, Malpighian tubules and fat body. In general, these organs ar...
ORGANISM(S): Drosophila melanogaster 
2014-09-20 | E-GEOD-32329 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of the ?mak-1 strain
The MAK-1 pathway is the least characterized MAP kinase pathway in Neurospora. Microarray analyses were carried out to identify genes with altered expression in ?mak-1 as compared to wild type strains. Mycelial mats of wild type and ?mak-1 strains were grown in constant light (LL) at 25C for 2 and ...
ORGANISM(S): Neurospora crassa 
2012-10-24 | E-GEOD-41778 | biostudies-arrayexpress
UnknownBritish societies guideline on the management of emergencies in patients on extracorporeal membrane oxygenation.
Not available
S-EPMC12640317 | biostudies-literature
MetabolomicsComparative non-targeted LC-MS metabolomic profiling of murine bone marrow-derived macrophages cultured in 2D versus 3D

Macrophages are key drivers of inflammatory and fibrotic diseases and their activation is shaped by interactions in their tissue microenvironment. However, dissecting the processes that drive immunopathology has proved challenging as traditional 2D culture methods fail to capture the complex mole...

2026-06-08 | MTBLS12917 | MetaboLights
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